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TranscriptomicsTranscription profiling of Xenopus laevis early embryos to investigate the roles of Nodal, Mixer and Sox17 in endoderm formation
A conserved molecular pathway has emerged controlling endoderm formation in Xenopus zebrafish and mice. Key genes in this pathway include Nodal ligands and transcription factors of the Mix-like paired homeodomain class, Gata4-6 zinc finger factors and Sox17 HMG domain proteins. While a linear epista...
ORGANISM(S): Xenopus laevis 
2007-10-05 | E-GEOD-4448 | biostudies-arrayexpress
GenomicsGenome-wide identification of putative cis-regulatory elements through epigenetic profiling in zebrafish
In this study, we have applied ChIP-Seq to identify putative regulatory elements throughout the zebrafish genome. For this purpose we identified sequences within the zebrafish genome that associate with H3K4me1 and H3K4me3, which are epigenetic modifications known to be associated with active cis-r...
ORGANISM(S): Danio rerio 
2011-02-25 | E-GEOD-20600 | biostudies-arrayexpress
TranscriptomicsIdentification of direct T-box target genes in the developing zebrafish mesoderm
The zebrafish genes spadetail (spt) and no tail (ntl) encode T-box transcription factors that are important for early mesoderm development. Although much has been done to characterize these genes, the identity and location of target regulatory elements remain largely unknown. Here, we survey the gen...
ORGANISM(S): Danio rerio 
2010-05-19 | E-GEOD-12857 | biostudies-arrayexpress
TranscriptomicsDynamic gene expression by putative hair-cell progenitors during regeneration in the zebrafish lateral line
Hearing loss is most commonly caused by the destruction of mechanosensory hair cells in the ear. This condition is usually permanent: Despite the presence of putative hair-cell progenitors in the cochlea, hair cells are not naturally replenished in adult mammals. Unlike those of the mammalian ear, t...
ORGANISM(S): Danio rerio 
2014-04-01 | E-GEOD-55853 | biostudies-arrayexpress
UnknownControversial issues in the management of patients with advanced prostate cancer: Results from a Canadian consensus forum.
Not available
S-EPMC7124178 | biostudies-literature
UnknownTreatment of Aspergillus fumigatus in patients with cystic fibrosis: a randomized, placebo-controlled pilot study.
Not available
S-EPMC3340414 | biostudies-literature
UnknownEffects of a short course of inhaled corticosteroids in noneosinophilic asthmatic subjects.
Not available
S-EPMC3267606 | biostudies-literature
UnknownCardiac Sarcoidosis multi-center randomized controlled trial (CHASM CS- RCT).
Not available
S-EPMC7367280 | biostudies-literature
UnknownRoutine lung volume recruitment in boys with Duchenne muscular dystrophy: a randomised clinical trial.
Not available
S-EPMC9340020 | biostudies-literature
UnknownTetherin promotes the innate and adaptive cell-mediated immune response against retrovirus infection in vivo.
Not available
S-EPMC4163935 | biostudies-literature
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