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MetabolomicsImpact of Visceral Leishmaniasis on Local Organ Metabolism in Hamsters
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ORGANISM(S): Mesocricetus auratus 
ST002347 | MetabolomicsWorkbench
TranscriptomicsCYP19A1 mediated sex hormone metabolism promotes severe disease outcome in SARS-CoV-2 infected male golden hamsters
Male sex belongs to one of the risk factors for severe COVID-19 outcome. However, underlying mechanisms that could affect sex dependent disease outcome are yet unknown. Here, we identified the CYP19A1 gene encoding for the testosterone-to-estradiol metabolizing enzyme CYP19A1 (alias aromatase) as a ...
ORGANISM(S): Mesocricetus auratus 
2022-01-21 | E-MTAB-11162 | biostudies-arrayexpress
TranscriptomicsChanges in the gene expression in the inferior colliculus of the sound stimulated both control Syrian hamsters and the strain GASH:Sal.
Using microarray analyses and subsequent verification by RT-PCR, we studied the changes in gene expression in the inferior colliculus after an ictal event in one models of audiogenic epilepsy, genetic audiogenic seizure hamster (GASH:Sal). GASH:Sal, a hamster strain developed at the University of Sa...
ORGANISM(S): Mesocricetus auratus 
2015-12-31 | E-GEOD-74043 | biostudies-arrayexpress
TranscriptomicsGenome-wide transcriptomic profiles of the lungs of SARS-CoV-2 infected hamsters treated with the CYP19A1 inhibitor letrozole.
Male and female golden hamsters (n = 5 per group) were either control (PBS) treated or infected with SARS-CoV-2 (105 pfu), following treatment with vehicle or the CYP19A1 (aromatase) inhibitor letrozole for 8 consecutive days. At 21 days post infection, animals were sacrificed; subsequently, the lun...
ORGANISM(S): Mesocricetus auratus 
2023-06-30 | E-MTAB-13100 | biostudies-arrayexpress
ProteomicsAntigen-specific IgG Glycosylation Profiles in Hamsters and Macaques Following COVID-19 Vaccination
Vaccination triggers the production of antigen-specific antibodies, including IgG. IgG molecules are glycosylated at the Fc region, and these glycan modifications markedly influence Fc receptor binding and downstream immune functions. Notably, infections with enveloped viruses such as SARS-CoV-2 can...
ORGANISM(S): Mesocricetus auratus (Golden hamster) Macaca mulatta (Rhesus macaque) 
2026-03-11 | PXD068257 | Pride
Glycosylation Antibody Sars-cov-2 Vaccination Covid-19 
TranscriptomicsDifferent developmental trajectories of ovaries in Siberian hamsters raised in long and short day lengths
A genome-wide association study was performed on ovaries from Siberian hamsters raised in either long or short photoperiod. Few differences between long and short photoperiod were noted at 3 wk of age, when ovarian histology was identical, whereas many differences in gene expression were noted at 8 ...
ORGANISM(S): Phodopus sungorus 
2013-09-14 | E-GEOD-50869 | biostudies-arrayexpress
ProteomicsHypolipidemic effects of Tamarindus indica fruit pulp extract
In this study, the hypolipidemic effects of Tamarindus indica fruit pulp extract (Tifpe) in the serum obtained from diet-induced hypercholesterolemic hamsters were investigated using two-dimensional gel electrophoresis and mass spectrometry. Significantly altered levels of serum proteins were valid...
ORGANISM(S): Mesocricetus auratus (Golden hamster) 
2018-10-04 | PXD010232 | Pride
Serum proteins Fruit pulp extract Tamarindus indica Hypolipidemia Hamsters 
GenomicsTranscriptome analysis of LepR knockout golden hamsters
Transcriptome analysis of LepR knockout golden hamsters
PRJNA1451078 | ENA
TranscriptomicsRNA-Seq of hamster PDAC cancer (HapT1 cell line) biopsies taken after treatment with either an IgG control or new hamster specific anti-PD-L1 monoclonal antibody.
1. The experiment was performed to assess if the newly discovered Syrian hamster specific anti-PD-L1 antibody could induce a biologically relevant change in transcriptome profile in the tumours. This would confirm that the antibody has functional properties. In the larger picture, the Syrian Hamster...
ORGANISM(S): Mesocricetus auratus 
2023-01-30 | E-MTAB-12297 | biostudies-arrayexpress
GenomicsMesocricetus auratus breed:Golden Syrian hamsters
Mesocricetus auratus breed:Golden Syrian hamsters Metagenomic assembly
PRJNA326307 | ENA
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