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MetabolomicsProfile of key metabolites and identification of HMGCS1-DHEA pathway in porcine Sertoli cells treated by Vitamin C
Vitamin C (Ascorbic acid, AA), as vital micro-nutrient, plays an essential role for male animal reproduction. Previously, we showed that vitamin C reprogrammed the transcriptome and proteome to change phenotypes of porcine immature Sertoli cells (iSCs). Here, we used LC-MS-based non-targeted metabol...
2024-07-31 | MTBLS9673 | MetaboLights
UnknownLack of association of -607 C/A and -137 G/C polymorphisms in interleukin 18 gene with susceptibility to gout disease in Chinese Han male population.
Not available
S-EPMC3364418 | biostudies-literature
TranscriptomicsSmall tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C
Small, non-coding RNAs control gene expression post-transcriptionally and play important roles in virus-host interactions. Within the liver, the microRNA (miRNA) miR-122 is essential for replication of hepatitis C virus (HCV), while repression of miR-148a by hepatitis B virus (HBV) may enhance tumor...
ORGANISM(S): Homo sapiens 
2014-12-18 | E-GEOD-57381 | biostudies-arrayexpress
ProteomicsC. elegans phosphoproteomics - DAF15 knockdown (The TORC1 phosphoproteome in C. elegans reveals roles in transcription and autophagy)
The protein kinase complex Target of Rapamycin complex 1 (TORC1) is a critical mediator of nutrient sensing that has been widely studied in cultured cells and yeast, yet our understanding of the regulatory activities of TORC1 in the context of a whole, multi-cellular organism is still very limited. ...
ORGANISM(S): Caenorhabditis elegans 
2022-04-22 | PXD032260 | Pride
Autophagy C. elegans Phosphoproteome Mtorc1 Daf-15 Raptor Mtor 
TranscriptomicsExpression data from the starved first larval stage (L1) C. elegans animals that were incubated in S-basal buffer for 30 hours after bleaching
How animals coordinate gene expression in response to starvation is an outstanding problem closely linked to aging, obesity, and cancer. Newly hatched Caenorhabditis elegans respond to food deprivation by halting development and promoting long-term survival (L1 diapause), thereby providing an excell...
ORGANISM(S): Caenorhabditis elegans 
2014-05-16 | E-GEOD-45651 | biostudies-arrayexpress
TranscriptomicsEffect of Ribavirin on Viral Kinetics and Liver Gene Expression in Chronic Hepatitis C
Background/Aims: Ribavirin improves treatment response to pegylated-interferon (PEG-IFN) in chronic hepatitis C but the mechanism remains controversial. We studied correlates of response and mechanism of action of ribavirin in treatment of hepatitis C. Methods: 70 treatment-naïve patients were rand...
ORGANISM(S): Homo sapiens 
2013-03-08 | E-GEOD-38663 | biostudies-arrayexpress
UnknownCase report: Novel GJB2 variant c.113T>C associated with autosomal recessive non-syndromic hearing loss (ARNSHL) in a Han family.
Not available
S-EPMC6922571 | biostudies-literature
GenomicsMeta-analysis Identifies MHC Loci in or near HLA-DRB1, HLA-DQA1, HLA-C as Associated with Leprosy in Chinese Han Population
Meta-analysis Identifies MHC Loci in or near HLA-DRB1, HLA-DQA1, HLA-C as Associated with Leprosy in Chinese Han Population
PRJNA488957 | ENA
UnknownFilaggrin gene mutation c.3321delA is associated with various clinical features of atopic dermatitis in the Chinese Han population.
Not available
S-EPMC4032331 | biostudies-literature
MetabolomicsTargeted rewiring of the rhizosphere metabolite-microbe axis restores phosphorus acquisition in inefficient citrus rootstocks
This study aimed to screen citrus rootstocks with contrasting phosphorus (P) efficiency. Seedlings were grown in P-deficient red soil-vermiculite substrate under greenhouse conditions. After 5 months cultivation, plant biomass, leaf P concentration, root architecture, rhizosphere available P and pho...
2026-10-22 | MTBLS15885 | MetaboLights
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