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ProteomicsQuantitative proteomic analysis of plasma in major mental disorders
Emerging high-throughput proteomic technologies have recently been considered as a powerful means of identifying substrates involved in mood disorders. We performed proteomic profiling using liquid chromatography-tandem mass spectrometry to identify dysregulated proteins in plasma samples of 44, 49,...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD028841 | Pride
Human Schizophrenia Plasma Bipolar disorder Mood depression disorder 
ProteomicsIn depth proteome analyais of primary human nasal epithelium induced by diesel exhaust particles
Diesel exhaust particles (DEPs), a major component of airborne particulate matter (PM), are strongly associated with the development of both acute and chronic upper airway inflammatory diseases. In this study, we investigated the effects of prolonged daily exposure to low-dose DEPs on the maturation...
ORGANISM(S): Homo sapiens (Human) 
2026-05-23 | PXD065940 | Pride
Diesel exhaust particles Human nasal epithelium Tmt 
ProteomicsUrinary proteomics anlaysis of Type 2 Diabetic Nephropathy
Type 2 Diabetic Nephropathy (T2DN), in the setting of type 2 diabetes, is the world占쎌뀼 leading cause of chronic kidney disease and end-stage kidney disease (ESKD). The increasing prevalence and heterogeneous phenotype of T2DN complicate the approach to treating patients. While kidney biopsy is the g...
ORGANISM(S): Homo sapiens (Human) 
2025-07-28 | PXD037505 | Pride
Urine Proteomics T2d 
ProteomicsComprehensive Proteomic Characterization of Human Pancreatic Cyst Fluid from Intraductal Papillary Mucinous Neoplasm by LC-MS/MS
Intraductal papillary mucinous neoplasm (IPMN) is a duct-dilating precancerous lesion that grows in pancreatic ducts and is accompanied by the production of mucinous fluid. In recent years, its cystic fluid has been used molecularly for the differential diagnosis of other cystic tumors and malignanc...
ORGANISM(S): Homo sapiens (Human) 
2017-08-22 | PXD005671 | Pride
Pancreatic cyst Protein mutation Intraductal papillary mucinous neoplasm 
ProteomicsMass spectrometry-based proteomics discovery of prognostic biomarkers in adrenal cortical carcinoma
Adrenal cortical carcinoma (ACC) is an extremely rare disease with a variable prognosis. Current prognostic markers have limitations in identifying patients with a poor prognosis. Herein, we aimed to investigate the prognostic protein biomarkers of ACC using mass-spectrometry-based proteomics. We pe...
ORGANISM(S): Homo sapiens (Human) 
2021-09-07 | PXD027404 | Pride
Human Ffpe Lfq Adrenal cortical carcinoma Biomarkers 
ProteomicsIn-depth quantitative proteomic analysis of rat cardiac tissue for exploring potential mediators of early cardiac reaioablation effect
Recently, stereotactic ablative radiotherapy (SABR) is adopted to noninvasively treat catheter ablation-refractory ventricular tachycardia (VT). VT episodes were dramatically reduced after SABR within few weeks, but underlying mechanisms of these clinical effects as well as potential mediator of ear...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-08-12 | PXD030878 | Pride
Rat Tmt Cardiac tissue Radiotherapy 
Proteomicsin-depth phosphoproteomic profiling of mouse microglia BV-2 cell line
We present a simple strategy (integrated Multistep enzyme digestion, Enrichment, Database search, “iMEED”) to improve coverage of the phosphoproteome from less starting material that is faster than other commonly used approaches. iMEED has generated the most comprehensive phosphoproteome of murine m...
ORGANISM(S): Mus musculus (Mouse) 
2014-10-15 | PXD001033 | Pride
Phosphoproteome Mouse Microglia Lc-ms/ms 
ProteomicsTMT quantitative proteomic analysis of craniopharyngioma tissues
Craniopharyngiomas are rare epithelial tumors derived from pituitary gland embryonic tissue. This epithelial tumor entity can be divided into the adamantinomatuous (ACP) and papillary (PCP) subtypes with the histomorphological and genetic differences. Genomic and transcriptomic profiles of craniopha...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD028790 | Pride
Human Tmt Craniopharyngioma Lc-ms/ms 
ProteomicsLabel-free quantitative proteomic analysis of craniopharyngioma tissues
Craniopharyngiomas are rare epithelial tumors derived from pituitary gland embryonic tissue. This epithelial tumor entity can be divided into the adamantinomatuous (ACP) and papillary (PCP) subtypes with the histomorphological and genetic differences. Genomic and transcriptomic profiles of craniopha...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD023376 | Pride
Human Craniopharyngioma Lfq 
ProteomicsQuantitative proteomic analysis of human malignant ascites
Ascites is a valuable source of cancer biomarkers, because it contains a variety of secreted and shed proteins from cancerous cells. Conversely, most proteomic studies on ascites have focused on ovarian cancer and provided insufficient depth for biomarker discovery. Further, no proteomic analysis of...
ORGANISM(S): Homo sapiens (Human) 
2018-04-16 | PXD004501 | Pride
Quantitative proteomics Gastric cancer Label-free quantitation Malignant ascites 
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