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ProteomicsHDX-MS analysis of a TTC7B specific nanobody to inhibit EFR3 mediated PI4KA recruitment
Phosphatidylinositol 4 kinase III (PI4KIII/PI4KA) is an essential lipid kinase that is critical for regulating plasma membrane identity. PI4KA is primarily recruited to the plasma membrane through targeted recruitment by the proteins EFR3A and EFR3B, with these binding to the PI4KA accessory protein...
ORGANISM(S): Homo sapiens (Human) 
2025-11-20 | PXD066213 | Pride
Pi4ka Hdx-ms Nanaobody Ttc7b 
MetabolomicsLongitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome

The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI) disorders. Determining its mechanistic role in disease has been difficult due to apparent disconnects between animal and human studies and lack of an integrated multi-omics view of disease-specific physiologica...

2020-09-08 | MTBLS1396 | MetaboLights
UnknownBiomarker Panel for Chronic Graft-Versus-Host Disease.
Not available
S-EPMC5012688 | biostudies-literature
UnknownGM-CSF primes cardiac inflammation in a mouse model of Kawasaki disease.
Not available
S-EPMC5030799 | biostudies-literature
MetabolomicshRUV: Hierarchical approach to removal of unwanted variation for large-scale metabolomics data
Liquid chromatography-mass spectrometry-based metabolomics studies are increasingly applied to large population cohorts, which run for several weeks or even years in data acquisition. This inevitably introduces unwanted intra- and inter-batch variations over time that can overshadow true biological ...
2021-07-05 | MTBLS2483 | MetaboLights
UnknownmTOR signalling controls the formation of smooth muscle cell-derived luminal myofibroblasts during vasculitis.
Not available
S-EPMC11467406 | biostudies-literature
GenomicsDNaseI Digital Genomic Footprinting from ENCODE/University of Washington [Human]
This data was generated by ENCODE. If you have questions about the data, contact the submitting laboratory directly (Richard Sandstrom mailto:sull@u.washington.edu). If you have questions about the Genome Browser track associated with this data, contact ENCODE (mailto:genome@soe.ucsc.edu). This tra...
ORGANISM(S): Homo sapiens 
2010-12-29 | E-GEOD-26328 | biostudies-arrayexpress
UnknownHydroxychloroquine and tocilizumab therapy in COVID-19 patients-An observational study.
Not available
S-EPMC7425928 | biostudies-literature
TranscriptomicsConservation of mouse-human trans-regulatory circuitry despite high cis-regulatory divergence
The basic body plan and major physiological axes have been highly conserved during mammalian evolution, yet only a small fraction of the human genome sequence appears to be subject to evolutionary constraint. To quantify cis- versus trans-acting contributions to mammalian regulatory evolution, we pe...
ORGANISM(S): Homo sapiens 
2014-11-19 | E-GEOD-51341 | biostudies-arrayexpress
UnknownA rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death.
Not available
S-EPMC4301587 | biostudies-literature
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