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TranscriptomicsM. catarrhalis Gene Expression in the Chinchilla Nasopharynx
M. catarrhalis strain O35E.rpsl was inoculated into the nasopharynx of healthy, male adult chinchillas. 24 hours later the nasopharyngeal tissues were extracted and homogenized. Total RNA was extracted from these tissue samples. Subsequently, M. catarrhalis genome directed primers were utilized t...
ORGANISM(S): Moraxella catarrhalis 
2012-04-03 | E-GEOD-13559 | biostudies-arrayexpress
TranscriptomicsIdentification of Gene Products Involved in the Oxidative Stress Response of Moraxella catarrhalis: Evaluation of OxyR dependent Genes
Series of DNA microarrays (4) comparing the M. catarrhalis strain 035E and M. catarrhalis oxyR mutant response to 50 mM hydrogen peroxide. Wild-type cells and oxyR mutant cells were exposed to 50 mM hydrogen peroxide for 15 minutes. RNA was extracted and DNA microarray analysis performed. 4 biologic...
ORGANISM(S): Moraxella catarrhalis 
2010-12-07 | E-GEOD-24351 | biostudies-arrayexpress
TranscriptomicsIdentification of Gene Products Involved in the Oxidative Stress Response of Moraxella catarrhalis
Series of DNA microarrays (4) comparing the M. catarrhalis strain 035E response to 50 mM hydrogen peroxide relative to a water-only control. Wild-type cells were exposed to either 50 mM hydrogen peroxide or a water-only control for 15 minutes. RNA was extracted and DNA microarray analysis performed...
ORGANISM(S): Moraxella catarrhalis 
2010-12-07 | E-GEOD-24331 | biostudies-arrayexpress
TranscriptomicsInteraction with Human Bronchial Epithelial Cells in vitro Affects Gene Expression in Moraxella catarrhalis
In this study, DNA microarray technology was used to measure global gene expression in M. catarrhalis cells that had attached to human bronchial epithelial cells in culture. M. catarrhalis ATCC 43617 was allowed to attach (MOI~30) to a monolayer of 16HBE14 human bronchial epithelial cells for 2 hr i...
ORGANISM(S): Moraxella catarrhalis 
2014-03-24 | E-GEOD-12990 | biostudies-arrayexpress
TranscriptomicsMicroRNA identity and abundance in porcine skeletal muscles determined by deep sequencing
MicroRNAs (miRNA) are short single-stranded RNA molecules that regulate gene expression post-transcriptionally by binding to complementary sequences in the 3' untranslated region (3' UTR) of target mRNAs. MiRNAs participate in the regulation of myogenesis, and identification of the complete set of m...
ORGANISM(S): Sus scrofa 
2009-11-24 | E-GEOD-14584 | biostudies-arrayexpress
MetabolomicsLongitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome

The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI) disorders. Determining its mechanistic role in disease has been difficult due to apparent disconnects between animal and human studies and lack of an integrated multi-omics view of disease-specific physiologica...

2020-09-08 | MTBLS1396 | MetaboLights
TranscriptomicsGene Expression differences in Hepatic Parenchyma and Portal Tracts in Hepatitis C Virus Infected Subjects with High and Low Fibrosis
Background & Aims: Chronic hepatitis C virus (HCV) infection is complicated by hepatic fibrosis. Hypothesizing that fibrogenic signals may originate in cells susceptible to HCV infection, gene expression of hepatocytes was analyzed from persons with chronic HCV at different stages of liver fibrosi...
ORGANISM(S): Homo sapiens 
2013-08-13 | E-GEOD-33650 | biostudies-arrayexpress
UnknownA hag mutant of Moraxella catarrhalis strain O35E is deficient in hemagglutination, autoagglutination, and immunoglobulin D-binding activities.
Not available
S-EPMC128162 | biostudies-literature
ProteomicsAlterations in Extracellular Matrix Composition during Aging and Photoaging of the Skin
Human skin is composed of the cell-rich epidermis, the extracellular matrix (ECM) rich dermis, and the hypodermis. Within the dermis, a dense network of ECM proteins provides structural support to the skin and regulates a wide variety of signaling pathways which govern cell proliferation and other c...
ORGANISM(S): Homo sapiens (Human) 
2020-07-03 | PXD015982 | Pride
Human skin proteomics lc-msms aging ecm 
ProteomicsComparative Proteomic Analysis of the Mycobacterium tuberculosis Lineage 7 Reveals Differentially Abundant Proteins Linked to Slow Growth
Differentially abundant proteins were quantified in the slowly growing Mycobacterium tuberculosis (M. tuberculosis) lineage 7 strains and the M. tuberculosis lineage 4 reference strain H37Rv. Mass spectrometry based proteomic analysis was employed to identify, quantitate and compare the protein pro...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2017-05-24 | PXD006117 | Pride
Proteomics Mycobacterium tuberculosis Tuberculosis Lineage 7 Mass spectrometry Ethiopia Type 7 secretion 
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