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ProteomicsNormoglycemia and physiological cortisone level maintain glucose homeostasis in a pancreas-liver microphysiological system
Current research on metabolic disorders and diabetes relies on animal models because multi-organ diseases cannot be well studied with the standard in vitro assays. Here, we connect models of key metabolic organs, pancreas and liver, on a microfluidic chip to enable diabetes research in a human-based...
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD052854 | Pride
Type 2 diabetes mellitus Metabolic disorders Microphysiological system Human pancreatic islets Glucocorticoids Hyperglycemia Transcriptomics Diabetes Proteomics Liver Pancreas 
TranscriptomicsFunctional tissue specific MSC in lung-transplanted patients with and without bronchiolitis obliterans syndrome (BOS) - a potential source for cell-therapy?
Background: Mesenchymal stromal cells (MSC) have been proposed as a future cell based therapy for lung diseases like bronchiolitis obliterans syndrome (BOS). Theoretically, it might be beneficial to use lung resident MSC already adapted to the pulmonary environment. We therefore aimed to compare lun...
ORGANISM(S): Homo sapiens 
2016-08-01 | E-GEOD-74163 | biostudies-arrayexpress
UnknownNeurocognition, cerebellar functions and psychiatric features in spinocerebellar ataxia type 34: a case series.
Not available
S-EPMC12722519 | biostudies-literature
ProteomicsTargeted Proteomics Using Stable Isotope Labeled Protein Fragments Enables Precise and Robust Determination of Total Apolipoprotein(a) in Human Plasma
Lipoprotein(a), also known as Lp(a), is an LDL-like particle composed of apolipoprotein(a) (apo(a)) bound covalently to apolipoprotein B100. Plasma concentrations of Lp(a) are highly heritable and vary widely between individuals. Elevated plasma concentration of Lp(a) is considered as an independent...
ORGANISM(S): Homo Sapiens 
2023-02-17 | PXD026976 | panorama
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