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Transactive response DNA-binding protein of 43 kDa (TDP-43), a heterogeneous nuclear ribonucleoprotein (hnRNP) with diverse activities, is a common denominator in several neurodegenerative disorders including amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). Orthologs...
ORGANISM(S): Caenorhabditis elegans 

Metabolites associated with the gut microbiota play an important role in the pathogenesis of choledocholithiasis concurrent with cholangitis (CC). This study aims to characterize the fecal metabolite profile of CC patients and to investigate the correlation and balance within the gut cross-domain...

2025-08-11 | MTBLS12772 | MetaboLights
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
Toxoplasma gondii is an obligate intracellular protozoan of severe threat to humans and livestock. Macrophages are the cell type preferentially infected by T. gondii in vivo. Protein phosphorylation is an important post-translational modification involved in diverse cellular functions. ARAF is membe...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2024-04-27 | PXD044725 | Pride
To understand the transcriptional program controlled by RGA, we took advantage of a functional steroid-inducible RGA proteins system in combination with microarray analysis to identify RGA target genes. Experiment Overall Design: We firstly compared the transcriptomes in ga1-3rgargl2RGA-GR infloresc...
ORGANISM(S): Arabidopsis thaliana 

Forest management in giant panda habitats necessitates strategies that simultaneously support biodiversity and ecosystem carbon sequestration. Here, we demonstrate that protecting understory vegetation is indispensable for sustaining the soil carbon sink in restored subalpine coniferous plantatio...

2025-12-02 | MTBLS13433 | MetaboLights
Here, we introduce a magnetic bead-based EV enrichment approach (EVrich) for automated and high-throughput processing of urine samples. Parallel enrichments can be performed in 96-well plates for downstream cargo analysis, including EV characterization, miRNA, proteomics and phosphoproteomics analys...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD033595 | Pride
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