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TranscriptomicsRNA-seq of coding RNA from USP14 knockout human haploid (HAP1) cells
We performed a genome-scale screen for suppressors of interferon stimulated gene (ISG) expression in human haploid cells (HAP1). Ubiquitin specific peptidase 14 (USP14) was a significant hit. In order to validate USP14 as a regulator of ISG expression, we created knockouts of USP14 in HAP1 cells usi...
ORGANISM(S): Homo sapiens 
2017-07-25 | E-MTAB-5865 | biostudies-arrayexpress
TranscriptomicsRNA-seq of coding RNA from DDX6 knockout human haploid (HAP1) cells
We performed a genome-scale screen for suppressors of interferon stimulated gene (ISG) expression in human haploid cells (HAP1). DEAD-box helicase 6 (DDX6) was a significant hit. In order to validate DDX6 as a regulator of ISG expression, we created knockouts of DDX6 in HAP1 cells using CRISPR-Cas9 ...
ORGANISM(S): Homo sapiens 
2017-07-25 | E-MTAB-5867 | biostudies-arrayexpress
TranscriptomicsIllumina RNA-seq of polyA+ RNA from HAP1 cells
Illumina RNA-seq was performed on polyA+ RNA isolated from the human HAP1 cell line
ORGANISM(S): Homo sapiens 
2019-03-14 | E-MTAB-7757 | biostudies-arrayexpress
GenomicsHomo sapiens strain:HAP1
HAP1 whole genome
PRJNA255446 | ENA
ProteomicsMissing proteins identified from the haploid cell lines: HAP1 and KBM-7
Chromosome-centric Human Proteomic Project (C-HPP) aims at identifying and characterizing protein products encoded from all protein-coding genes of human chromosomes. As evident in the recent nature papers, it is possible that those missing proteins may be low abundant in many cell types or expresse...
ORGANISM(S): Homo sapiens (Human) 
2018-10-01 | PXD006614 | Pride
Lc-msms Missing proteins Kbm-7 Haploid cell line Hap1 
ProteomicsMissing proteins identified from the haploid cell lines: HAP1 and KBM-7
Chromosome-centric Human Proteomic Project (C-HPP) aims at identifying and characterizing protein products encoded from all protein-coding genes of human chromosomes. As evident in the recent nature papers, it is possible that those missing proteins may be low abundant in many cell types or expresse...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-10 | MSV000083952 | MassIVE
GenomicsChIP-seq of Pol III and H3K4me3 in HAP1 and HepG2 tRNA gene deletion clones and control clones
This dataset contains ChIP-seq data of H3K4me3 and Pol III in single cell-derived control and CRISPR/Cas9 induced tRNA gene deletion clones in human cancer cell lines HAP1 and HepG2. In this study, we looked into functional Cas9-induced on-target genomic alteration in our tRNA gene deletion clones, ...
ORGANISM(S): Homo sapiens 
2022-09-16 | E-MTAB-10651 | biostudies-arrayexpress
GenomicsChIP-seq of H3K27ac and H3K4me3 in HAP1 tRNA gene locus modified clones and control clones
This dataset contains ChIP-seq data profiling genomic binding of H3K27ac and H3K4me3 in single cell-derived control, as well as CRISPR/Cas9 induced tRNA gene deletion clones and intergenic region deletion clones in human cancer cell lines HAP1. In this study, we found a large genomic deletion of 10q...
ORGANISM(S): Homo sapiens 
2023-10-24 | E-MTAB-11859 | biostudies-arrayexpress
GenomicsChIPmentation of FKBP12(F36V)-ZNF24 HAP1 cells treated with dTAGv-1 to induce endogenous ZNF24 degradation
Human HAP1 cell lines with their endogenous ZNF24 gene tagged with an FKBP12(F36V) degron were treated with dTAGv-1 to induce endogenous ZNF24 degradation to study the role of ZNF24 on histone modifications.
ORGANISM(S): Homo sapiens 
2026-08-01 | E-MTAB-14699 | biostudies-arrayexpress
OtherHuntingtin associated protein (HAP1) is a cGMP-dependent kinase anchoring protein (GKAP), specific for the cGMP-dependent protein kinase Iβ isoform.
Data from ProteomeXchange, PXD ID: PXD001434. Published as part of J Biol Chem. 2015 Feb 4. pii . From the Abstract: {{i}} ... Here, we extend on this cAMP-based chemical proteomics approach, employing competitive concentrations of free cyclic nucleotides to isolate each kinase and its secondary in...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32320007631 | GPMDB
Resource Reanalysis 
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