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ProteomicsMissing proteins identified from the haploid cell lines: HAP1 and KBM-7
Chromosome-centric Human Proteomic Project (C-HPP) aims at identifying and characterizing protein products encoded from all protein-coding genes of human chromosomes. As evident in the recent nature papers, it is possible that those missing proteins may be low abundant in many cell types or expresse...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-10 | MSV000083952 | MassIVE
TranscriptomicsIllumina RNA-seq of polyA+ RNA from HAP1 cells
Illumina RNA-seq was performed on polyA+ RNA isolated from the human HAP1 cell line
ORGANISM(S): Homo sapiens 
2019-03-14 | E-MTAB-7757 | biostudies-arrayexpress
ProteomicsMissing proteins identified from the haploid cell lines: HAP1 and KBM-7
Chromosome-centric Human Proteomic Project (C-HPP) aims at identifying and characterizing protein products encoded from all protein-coding genes of human chromosomes. As evident in the recent nature papers, it is possible that those missing proteins may be low abundant in many cell types or expresse...
ORGANISM(S): Homo sapiens (Human) 
2018-10-01 | PXD006614 | Pride
Lc-msms Missing proteins Kbm-7 Haploid cell line Hap1 
TranscriptomicsRNA-seq of coding RNA from USP14 knockout human haploid (HAP1) cells
We performed a genome-scale screen for suppressors of interferon stimulated gene (ISG) expression in human haploid cells (HAP1). Ubiquitin specific peptidase 14 (USP14) was a significant hit. In order to validate USP14 as a regulator of ISG expression, we created knockouts of USP14 in HAP1 cells usi...
ORGANISM(S): Homo sapiens 
2017-07-25 | E-MTAB-5865 | biostudies-arrayexpress
TranscriptomicsRNA-seq of coding RNA from DDX6 knockout human haploid (HAP1) cells
We performed a genome-scale screen for suppressors of interferon stimulated gene (ISG) expression in human haploid cells (HAP1). DEAD-box helicase 6 (DDX6) was a significant hit. In order to validate DDX6 as a regulator of ISG expression, we created knockouts of DDX6 in HAP1 cells using CRISPR-Cas9 ...
ORGANISM(S): Homo sapiens 
2017-07-25 | E-MTAB-5867 | biostudies-arrayexpress
ProteomicsCell Surface Glycoengineering - HAP1 Cells
Cell Surface Glycoengineering of HAP1 Cells using CMP-Neu5Ac Derivatives
ORGANISM(S): Homo sapiens (Human) 
2022-06-26 | PXD024251 | Pride
Cell surface glycoengineering - hap1 cells 
GenomicsChIP-seq of Pol III and H3K4me3 in HAP1 and HepG2 tRNA gene deletion clones and control clones
This dataset contains ChIP-seq data of H3K4me3 and Pol III in single cell-derived control and CRISPR/Cas9 induced tRNA gene deletion clones in human cancer cell lines HAP1 and HepG2. In this study, we looked into functional Cas9-induced on-target genomic alteration in our tRNA gene deletion clones, ...
ORGANISM(S): Homo sapiens 
2022-09-16 | E-MTAB-10651 | biostudies-arrayexpress
GenomicsChIP-seq of H3K27ac and H3K4me3 in HAP1 tRNA gene locus modified clones and control clones
This dataset contains ChIP-seq data profiling genomic binding of H3K27ac and H3K4me3 in single cell-derived control, as well as CRISPR/Cas9 induced tRNA gene deletion clones and intergenic region deletion clones in human cancer cell lines HAP1. In this study, we found a large genomic deletion of 10q...
ORGANISM(S): Homo sapiens 
2023-10-24 | E-MTAB-11859 | biostudies-arrayexpress
GenomicsChIPmentation of FKBP12(F36V)-ZNF24 HAP1 cells treated with dTAGv-1 to induce endogenous ZNF24 degradation
Human HAP1 cell lines with their endogenous ZNF24 gene tagged with an FKBP12(F36V) degron were treated with dTAGv-1 to induce endogenous ZNF24 degradation to study the role of ZNF24 on histone modifications.
ORGANISM(S): Homo sapiens 
2026-08-01 | E-MTAB-14699 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of human haploid cells (HAP1) depleted of SMARCB1 and SMARCA4
The aim of this study is to analyze the change in genome wide expression levels in HAP1 cells upon loss of SMARCB1, SMARCA4 or both these genes together. The SMARCB1 and SMARCA4 genes were the hits from a genome wide screen involving genetrap mutagenesis to find new players that are involved in sen...
ORGANISM(S): Homo sapiens 
2016-08-22 | E-GEOD-75515 | biostudies-arrayexpress
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