Sort   by:  
 Page size 
TranscriptomicsPlasmodesmal closure triggers stress responses
We generated two independent genetic tools that can induce callose deposition and plasmodesmal closure following estradiol treatment: LexA::Icals3m and LexA::PLUG. We harvested mature leaf tissue at 12h, 24h, 48h and 72h post induction and extracted total RNA
ORGANISM(S): Arabidopsis thaliana 
2026-03-31 | E-MTAB-16776 | biostudies-arrayexpress
TranscriptomicsRNA-sequencing of transgenic Arabidopsis seedlings constitutively expressing a Colletotrichum higginsianum effector
The fungal pathogen Colletotrichum higginsianum secretes effector proteins during infection of Arabidopsis. To explore the host processes perturbed by the effector candidate ChEC108 in host plants, transgenic Arabidopsis lines were generated to express AtUBQ10pro:ChEC108-eGFP or AtUBQ10pro:ChEC108^D...
ORGANISM(S): Arabidopsis thaliana 
2026-05-21 | E-MTAB-16996 | biostudies-arrayexpress
TranscriptomicsThe transcriptome of TRPV1-positive sensory neurons revealed by subgroup-elimination transcriptomics
We developed an approach to rapidly eliminate the subgroup of sensory neurons expressing the heat-gated cation channel TRPV1 from dissociated rat sensory ganglia using agonist treatment followed by density centrifugation. To identify transcripts predomintly expressed in TRPV1-positive neurons, we co...
ORGANISM(S): Rattus norvegicus 
2015-05-12 | E-GEOD-59727 | biostudies-arrayexpress
TranscriptomicsExpression analysis in mouse female PGK12.1 ES cells by RNA-seq
Many animal species employ a chromosome-based mechanism of sex determination, which has led to coordinate evolution of dosage compensation systems. Dosage compensation not only corrects the imbalance in the number of X-chromosomes between the sexes, but is also hypothesized to correct dosage imbalan...
ORGANISM(S): Mus musculus 
2011-07-19 | E-GEOD-30690 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human head and neck squamous cell carcinomas that are positive or negative for Human Papilloma Virus
Introduction: Human Papilloma Virus (HPV) is associated with a subset of head and neck squamous cell carcinoma (HNSCC), between 15% and 35% of HNSCC harboring HPV, almost exclusively of subtype 16. Demographic and exposure differences between HPV-positive (+) and negative (-) HNSCCs suggest that HPV...
ORGANISM(S): Homo sapiens 
2007-09-20 | E-GEOD-3292 | biostudies-arrayexpress
TranscriptomicsRNA-seq of MYC-Low and MYC-High FC-MYC Cells Following SUMOylation Inhibition with SAEi ML-792
The synthetic lethal relationship between MYC and SAE2 has been previously described in FC-MYC cells using RNAi (Littler et al., 2019). Building on this work, we conducted transcriptomic analysis on MYC-low and MYC-high cells following inhibition of SUMOylation with the SAE1/2 inhibitor, ML-792 (SAE...
ORGANISM(S): Homo sapiens 
2025-04-01 | E-MTAB-14654 | biostudies-arrayexpress
TranscriptomicsA search for small noncoding RNAs in Staphylococcus aureus reveals a conserved sequence motif for regulation.
Analysis of the intergenic regions of Staphylococcus aureus by bioinformatics predicted multiple regulatory regions. From this analysis, we also characterized 11 novel noncoding RNAs (RsaA-K) that are expressed in several S. aureus strains under different experimental conditions. Many of them accumu...
ORGANISM(S): Staphylococcus aureus 
2010-05-18 | E-GEOD-17135 | biostudies-arrayexpress
TranscriptomicsEpigenetic portraits of human breast cancers (methylation data)
Breast cancer is a molecularly, biologically and clinically heterogeneous group of disorders. Understanding this diversity is essential to improving diagnosis and optimising treatment. Both genetic and acquired epigenetic abnormalities participate in cancer, but information is scant on the involveme...
ORGANISM(S): Homo sapiens 
2011-10-18 | E-GEOD-20712 | biostudies-arrayexpress
TranscriptomicsEpigenetic portraits of human breast cancers (methylation data 2)
Breast cancer is a molecularly, biologically and clinically heterogeneous group of disorders. Understanding this diversity is essential to improving diagnosis and optimising treatment. Both genetic and acquired epigenetic abnormalities participate in cancer, but information is scant on the involveme...
ORGANISM(S): Homo sapiens 
2011-10-18 | E-GEOD-22249 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryonic stem cell line mESC D3 reveals cardiac differentiation of embryonic stem cells recapitulates embryonic cardiac development.
Mouse embryonic stem cells can differentiate in vitro into spontaneously contracting cardiomyocytes. The main objective of this study was to investigate cardiogenesis in cultures of differentiating embryonic stem cells (ESCs) and to determine how closely it mimics in vivo cardiac development. We ide...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-5671 | biostudies-arrayexpress
Sort   by:  
 Page size