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UnknownNeurocognitive Functioning of Children Treated for High-Risk B-Acute Lymphoblastic Leukemia Randomly Assigned to Different Methotrexate and Corticosteroid Treatment Strategies: A Report From the Children's Oncology Group.
Not available
S-EPMC5549456 | biostudies-literature
TranscriptomicsNext Generation Sequencing Identifies Differentially Expressed Genes in Zebrafish Embryos and Larvae Following Benzo[a]pyrene Exposure
Purpose: This study aimed to identify differentially expressed genes and transcripts in zebrafish embryos and larvae following benzo[a]pyrene (BaP) exposure. Methods: Adult zebrafish (2 males × 4 females, N=6 replicate tanks for each treatment) were acclimated for 7 days in an 818 Low Temp Illuminat...
ORGANISM(S): Danio rerio 
2015-09-04 | E-GEOD-64198 | biostudies-arrayexpress
TranscriptomicsmiR-122 as a Regulator of Mitochondrial Metabolic Gene Network in Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the leading cause of cancer-related deaths worldwide, reflecting the need for a better understanding of hepatocarcinogenesis. In this study, we examined the genome-wide expression profiles of both miRNAs and mRNAs from paired tumor and adjacent non-tumor tissues fro...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-22058 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human macrophages and dendritic cells exposed to phylogenetically distinct parasites
Monocyte-derived dendritic cells (DC) and macrophages (MΦ) generated in vitro from the same individual blood donors were exposed to five different pathogens, and gene expression profiles were assessed by microarray analysis. Responses to Mycobacterium tuberculosis and to phylogenetically distinct ...
ORGANISM(S): Homo sapiens 
2007-12-13 | E-GEOD-360 | biostudies-arrayexpress
TranscriptomicsGene expression of triclosan susceptible and tolerant E. coli O157:H19 in response to triclosan exposure
Triclosan is a biocidal active agent commonly found in domestic cleaning products, hand sanitizers, cosmetics and personal care products. It is used to control microbial contamination and has a broad-spectrum of activity against many Gram-positive and Gram-negative bacteria. The development of tricl...
ORGANISM(S): Escherichia coli O157:H7 
2013-10-15 | E-GEOD-39343 | biostudies-arrayexpress
TranscriptomicsLipopolysaccharide modulates rhinovirus-induced chemokine secretion in monocytes and macrophages.
Rhinovirus (RV) infection has been shown to exacerbate asthma. Understanding of the underlying mechanisms by which RV infections provoke airway inflammation and remodeling in asthma may offer significant insight into asthma pathogenesis and exacerbations as well as offer opportunities for improved d...
ORGANISM(S): Homo sapiens 
2014-01-31 | E-GEOD-54558 | biostudies-arrayexpress
UnknownSomatic mutations of the histone H3K27 demethylase gene UTX in human cancer.
Not available
S-EPMC2873835 | biostudies-literature
TranscriptomicsArray results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol
RELEVANCE: Smith-Lemli-Opitz syndrome (SLOS) is a human disease caused by mutations in the gene coding for the enzyme DHCR7 (7-dehydrocholesterol (7DHC) reductase), which catalyzes the final step of cholesterol biosynthesis. Accumulated 7DHC in tissues and body fluids of SLOS patients gives rise t...
ORGANISM(S): Mus musculus 
2021-03-20 | E-MTAB-10055 | biostudies-arrayexpress
TranscriptomicsNetwork Analysis Reveals a Novel Role for the AP-1 Transcription Factor JUNB in Classical and Alternative Macrophage Activation
Bone marrow-derived macrophages were generated from wild type and Junb knockout mice and tested for their responses to LPS treatment. Independent replicate wells from wild type and knockout bone marrow-derived macrophages were mock-treated or LPS-treated. RNA was isolated at 4 h post-treatment, ampl...
ORGANISM(S): Mus musculus 
2014-12-22 | E-GEOD-50542 | biostudies-arrayexpress
UnknownRich club analysis in the Alzheimer's disease connectome reveals a relatively undisturbed structural core network.
Not available
S-EPMC4504816 | biostudies-literature
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