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MetabolomicsIntegrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency
Functional oncogenic links between ErbB2 and ERRα in HER2+ breast cancer patients support a therapeutic benefit of co-targeted therapies. However, ErbB2 and ERRα also play key roles in heart physiology, and this approach could pose a potential liability to cardiovascular health. Herein, using integr...
2022-09-20 | MTBLS795 | MetaboLights
TranscriptomicsInvestigation of barley brittle stem mutants
The barley brittle stem mutants, fs2, designated X054 and M245, have reduced levels of cellulose compared with their isogenic parents Ohichi and Shiroseto. A custom-designed microarray, based on Agilent technology and including genes involved in cell wall metabolism, was used to compare transcript ...
ORGANISM(S): Hordeum vulgare 
2010-07-23 | E-GEOD-17873 | biostudies-arrayexpress
TranscriptomicsHepatic miRNA profiles and thyroid hormone homeostasis in rats exposed to dietary potassium perfluorooctanesulfonate (PFOS) [mRNA]
Perfluorooctanesulfonate (PFOS) has been widely used in a variety of industrial and commercial applications as a surfactant and stain repellent. PFOS causes liver damage (including liver tumors) in experimental animals, primarily via interaction with PPARa and CAR/PXR. We investigated the involvemen...
ORGANISM(S): Rattus norvegicus 
2015-08-01 | E-GEOD-69520 | biostudies-arrayexpress
UnknownValidation of a Prediction Tool for Chemotherapy Toxicity in Older Adults With Cancer.
Not available
S-EPMC5321104 | biostudies-literature
UnknownMulti-Institutional Phase II Study of High-Dose Hypofractionated Proton Beam Therapy in Patients With Localized, Unresectable Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma.
Not available
S-EPMC4872014 | biostudies-literature
ProteomicsA Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia...
3xFLAG-IPs from HEK293T cell lysates expressing 3xFLAG-bait or 3xFLAG-control. Trypsin Digestion
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-04-09 | MSV000079100 | MassIVE
UnknownAllopregnanolone as an Adjunct Therapy to Midazolam is More Effective Than Midazolam Alone in Suppressing Soman-Induced Status Epilepticus in Male Rats.
Not available
S-EPMC11871396 | biostudies-literature
TranscriptomicsTrans. Profiling of Immortalized Melanocyte Cell Lines Identifies GPNMB as a Melanoblast-Expressed, MITF-Dependent Gene
Gene expression profiling of tissues derived from different genetic backgrounds can provide insight to potential phenotype-related changes in gene expression. We have compared wildtype C57BL/6 (melan-Ink4a) melanocyte cell gene expression to that of, “brown“ Tyrp1b/ b (melan-Ink4a-b) and “cho...
ORGANISM(S): Mus musculus 
2010-05-19 | E-GEOD-10163 | biostudies-arrayexpress
TranscriptomicsVaccination against yersiniosis induces a specific gill transcriptome biosignature in Atlantic salmon
Simple cost-effective bacterins are the earliest and most successfully used commercial vaccines in fish. In particular, those prepared from Yersinia ruckeri have proven effective at controlling Enteric Red Mouth Disease (ERM) and yersiniosis in rainbow trout and Atlantic salmon, respectively. Howeve...
ORGANISM(S): Salmo salar 
2012-07-21 | E-GEOD-36332 | biostudies-arrayexpress
UnknownSingle-cell transcriptomics of suprachiasmatic nuclei reveal a Prokineticin-driven circadian network
Not available
S-SCDT-EMBOJ-2021-108614 | biostudies-other
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