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MetabolomicsMultiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment
Membrane lipids and their metabolism have key functions in neurotransmission. Here we provide a quantitative lipid inventory of mouse and rat synaptic junctions. To this end, we developed a multiomics extraction and analysis workflow to probe the interplay of proteins and lipids in synaptic signal t...
2021-09-27 | MTBLS1531 | MetaboLights
ProteomicsMulti-omics reveals the lipid inventory of synaptic junctions and altered lipid signaling in environmental enrichment
Membrane lipids are essential components of synaptic junctions that have key functions in neurotransmission. In the first part of the study, we provide a quantitative lipid inventory of mouse and rat synaptic junctions. We next used a simultaneous multi-omics extraction and analysis workflow termed ...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2023-11-14 | PXD017997 | Pride
Enriched environment Lipidomics Multi-omics Endocannabinoid signaling Synaptic junctions 
UnknownLentinula edodes Cultured Extract and Rouxiella badensis subsp. acadiensis (Canan SV-53) Intake Alleviates Immune Deregulation and Inflammation by Modulating Signaling Pathways and Epigenetic Mechanisms.
Not available
S-EPMC10572597 | biostudies-literature
UnknownChemical Composition and Biological Activity of Commelina erecta: An Edible Wild Plant Consumed in Brazil.
Not available
S-EPMC9818490 | biostudies-literature
UnknownAltered regulation of cardiac ankyrin repeat protein in heart failure.
Not available
S-EPMC5857524 | biostudies-literature
ProteomicsResolving human α versus β cell fate allocation for the generation of stem cell-derived islets
Generating stem cell-derived glucagon-producing α and insulin-producing β cells allows to engineer in vitro biomimetics of the islet of Langerhans, the micro-organ controlling blood glucose; however, there is still a major knowledge gap in the mechanism by which human stem cell-derived α and β cells...
ORGANISM(S): Homo sapiens (Human) 
2026-05-19 | PXD064617 | Pride
Lc-msms 
UnknownThe significant impact of meconium ileus on clinical outcomes among Brazilian individuals with cystic fibrosis-a retrospective analysis of a patient registry.
Not available
S-EPMC12435481 | biostudies-literature
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