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ProteomicsN-glycoproteomics of CHO cell-expressed FGFR3
Receptor tyrosine kinases (RTKs) that undergo N-linked glycosylation undergo protein quality control in the endoplasmic reticulum (ER) and subsequently transfer to the Golgi apparatus, where they acquire a diverse array of glycan structures. The family of receptor tyrosine kinases (RTKs) known as FG...
ORGANISM(S): Homo sapiens (Human) 
2026-08-05 | PXD047309 | Pride
Fgfr3 Fibroblast growth factor receptor 3 N-glycoproteomics 
Proteomicshepatocyte grwoth factor receptor (MET) LC-MSMS
MET, the receptor for hepatocyte growth factor (HGF), is involved in wide variety of biological events and its aberrant activation is implicated in the pathogenesis of cancer. Especially, MET signaling is associated with resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor...
ORGANISM(S): Homo sapiens (Human) 
2023-04-07 | PXD029295 | Pride
Glycosylation Hepatocyte grwoth factor receptor (met) 
ProteomicsSite-specific glycan analysis of epidermal growth factor receptor 2
This study provides site-specific profiles of asparagine-linked and serine/threonine-linked glycosylations on ErbB2, a therapeutic target RTK for ErbB2-positive cancer, through structural analysis of recombinant ErbB2 extracellular region and endogenous ErbB2 from ErbB2-positive breast cancer cells....
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD039834 | Pride
Glycosylation Erbb2 Her2 
ProteomicsSite-specific glycan analysis of epidermal growth factor receptor (EGFR)
This study provides site-specific profiles of asparagine-linked and serine/threonine-linked glycosylations on ErbB2, a therapeutic target RTK for ErbB2-positive cancer, through structural analysis of recombinant ErbB2 extracellular region and endogenous ErbB2 from ErbB2-positive breast cancer cells....
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD039836 | Pride
Glycosylation Egfr 
ProteomicsSite-specific glycan analysis of CHO cell expressed epidermal growth factor receptor 2
This study provides site-specific profiles of asparagine-linked and serine/threonine-linked glycosylations on ErbB2, a therapeutic target RTK for ErbB2-positive cancer, through structural analysis of recombinant ErbB2 extracellular region and endogenous ErbB2 from ErbB2-positive breast cancer cells....
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD039835 | Pride
Glycosylation Erbb2 Her2 
ProteomicsSite-specific glycan analysis of ErbB2 in breast cancer cell BT474
This study provides site-specific profiles of asparagine-linked and serine/threonine-linked glycosylations on ErbB2, a therapeutic target RTK for ErbB2-positive cancer, through structural analysis of recombinant ErbB2 extracellular region and endogenous ErbB2 from ErbB2-positive breast cancer cells....
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD039838 | Pride
Breast cancer Erbb2 Her2 
ProteomicsSite-specific glycan analysis of ErbB2 in breast cancer cell SKBR-3
This study provides site-specific profiles of asparagine-linked and serine/threonine-linked glycosylations on ErbB2, a therapeutic target RTK for ErbB2-positive cancer, through structural analysis of recombinant ErbB2 extracellular region and endogenous ErbB2 from ErbB2-positive breast cancer cells.
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD039837 | Pride
Breast cancer Glycosylation Erbb2 Her2 
TranscriptomicsSignificance of SALL4 as a drug resistant factor in lung cancer
To examine the mechanism by which SALL4 regulates drug sensitivity, approximately 65,000 molecules on a microarray chip were analyzed using lung cancer cells transduced with a SALL4 vector (pCMV6-SALL4) or a control vector (pCMV6-Mock) . SALL4 mRNA and protein expression markedly increased after 24 ...
ORGANISM(S): Homo sapiens 
2014-04-30 | E-GEOD-56595 | biostudies-arrayexpress
ProteomicsProteome and peptidome analyses of mouse caecal contents and Paraprevotella clara culture supernatants
Caecal contents from three specific pathogen-free (SPF) mice, and three germ-free (GF) mice were analyzed by DIA-MS (SWATH-MS) using TripleTOF 5600+ (SCIEX). Paraprevotella clara (P. clara) culture supernatants nontreated and treated tunicamycin or 2-fluro-L-fucose (2F-Fuc) were analyzed by DIA-MS u...
ORGANISM(S): Paraprevotella Clara Mus Musculus (mouse) 
2022-06-29 | PXD027678 | JPOST Repository
ProteomicsIdentification of complex of Paraprevotella clara 00502 protein and human PRSS2
00502 protein derived from Paraprevotella clara, as well as mixture of 00502 protein and human PRSS2 were analyzed by Native-PAGE. The observed bands were cut out and digested in-gel. The digested peptides were analyzed by DDA-MS using Q Exactive HF-X .
ORGANISM(S): Paraprevotella Clara 
2022-06-29 | PXD032242 | JPOST Repository
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