Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of human BJ fibroblasts after LIN-9 depletion by a shRNA
Aim: identification of differentially expressed genes after LIN-9 depletion.

hTERT immortalized human BJ fibroblasts were infected with pMSCV-Blasticidin based retroviruses encoding a shRNA which targets human LIN-9 and the empty vector respectively.
After 4 days of selection total RNA ...
ORGANISM(S): Homo sapiens 
2006-11-23 | E-MEXP-752 | biostudies-arrayexpress
ProteomicsVitreous proteome of transgenic INSC94Y pigs compared to wild type
INSC94Y transgenic pigs serve as a valuable model for permanent neonatal diabetes mellitus. Through genetically engineered modifications in the insulin (INS) gene, this model presents with impaired insulin secretion, resulting elevated fasting blood-glucose levels (hyperglycemia) [1].One of the seve...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2024-08-27 | PXD038198 | Pride
Quantitative label-free lc-ms/ms  diabetes mellitus  permanent neonatal diabetes  diabetic retinopathy  genetically modified pig  insc94y  porcine model  vitreous 
ProteomicsThe proteome of native adult Müller cells from the murine retina
We set out to first establish and validate a novel rapid method of enriching adult Müller cells, which yields sufficient cell numbers for proteomic profiling while keeping cells viable and morphologically, as well as physiologically fully intact. From these preparations we collected a comprehensive ...
ORGANISM(S): Mus musculus (Mouse) 
2016-08-15 | PXD002247 | Pride
Lc-msms Macs Retina Fasp Muller glia cell 
TranscriptomicsTranscription profiling of mouse embyronic fibroblasts from wild type and Lin9 knockout strains treated with 4-hydroxytestosterone
We used microarrays to analyze the role of Lin9 in gene expression. Experimental overall design: We prepared MEFs from embyos containing a conditional allele of Lin9 and a CreERT2 transgene. Transcriptional profiles of untreated and 4-OHT-treated MEFs were compared.
ORGANISM(S): Mus musculus 
2010-03-31 | E-MEXP-2097 | biostudies-arrayexpress
ProteomicsAltered porcine PBMC proteome and secretome after stimulation with BanLec
With this experiment, we aimed at showing changes in the proteome and secretome of porcine peripheral blood mononuclear cells (PBMC) after stimulation with Banana Lectin (BanLec).
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2021-08-26 | PXD027505 | Pride
Pbmc Musa banana Polyclonal cell stimulation Banlec Plant lectin Pig Lc-ms/ms 
Sort   by:  
 Page size