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ProteomicsN-glycan profiling of Pseudomyxoma peritonei
Pseudomyxoma peritonei (PMP) is a subtype of mucinous adenocarcinoma of the appendix, We compared N-linked glycan profiles of PMP tissues to those of normal appendix. N-glycosidase F liberated N-glycan profiles of eight normal appendix samples and eight low-grade and eight high-grade PMP specimens w...
ORGANISM(S): Homo sapiens (Human) 
2018-08-03 | PXD010086 | Pride
Human appendix cancer n-glycan fucosylation 
ProteomicsN-glycomic profiling of colorectal cancer according to tumor stage and location
Alterations in glycosylation are seen in many types of cancer, including colorectal cancer (CRC). CRC is known to display glycosylation alterations. Glycans, the sugar moieties of glycoconjugates, are involved in many important functions relevant to cancer, such as cell signaling and adhesion, and m...
ORGANISM(S): Homo sapiens (Human) 
2020-06-10 | PXD018673 | Pride
N-glycan cancer maldi-tof mass spectrometry 
TranscriptomicsGene expression profiling classifies lung squamous cell carcinomas with N1 positive lymph nodes
Using gene expression microarrays, we tested whether lung SCCs that have metastasised to loco-regional lymph nodes (N1/2m) are different to those that directly invade and involve local nodes (N1d). Using 22,323 element microarrays, a non-parametric test identified 126 genes/transcripts that discrimi...
ORGANISM(S): Homo sapiens 
2007-05-01 | E-GEOD-5828 | biostudies-arrayexpress
TranscriptomicsWhole genome expression array profiling highlights differences in mucosal defense genes in Barrett's esophagus and esophageal adenocarcinoma.
Esophageal adenocarcinoma (EAC) has become a major concern in Western countries due to rapid rises in incidence coupled with very poor survival rates. One of the key risk factors for the development of this cancer is the presence of Barrett’s esophagus (BE), which is believed to form in response to ...
ORGANISM(S): Homo sapiens 
2011-08-16 | E-GEOD-28302 | biostudies-arrayexpress
UnknownMulti-Site N-glycan mapping study 1: Capillary electrophoresis - laser induced fluorescence.
Not available
S-EPMC4966509 | biostudies-literature
UnknownThe N-terminal intrinsically disordered domain of Mgm101p is localized to the mitochondrial nucleoid.
Not available
S-EPMC3572067 | biostudies-literature
TranscriptomicsPenetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression (3)
Biallelic mutations of the DNA annealing helicase SMARCAL1 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin, subfamily a-like 1) cause Schimke immuno-osseous dysplasia (SIOD, MIM 242900), an incompletely penetrant autosomal recessive disorder. Using human, Drosophila, and mo...
ORGANISM(S): Mus musculus 
2012-04-04 | E-GEOD-35553 | biostudies-arrayexpress
UnknownThe effect of the TRF2 N-terminal and TRFH regions on telomeric G-quadruplex structures.
Not available
S-EPMC2655686 | biostudies-literature
TranscriptomicsLipid-mediated steatosis sensitises hepatocytes to the adverse effects of doxorubicin
The incidence of obesity and its related morbidities has rapidly increased over the past twenty years. One consequence of this is the increased probability of having to treat obese individuals for breast cancer. An important co-morbidity associated with obesity are the spectrum of fatty liver diseas...
ORGANISM(S): Homo sapiens 
2015-06-01 | E-MTAB-3523 | biostudies-arrayexpress
UnknownGenome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151).
Not available
S-EPMC4879186 | biostudies-literature
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