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Transcriptomicshcf-1(-) transcriptional profiling
We used microarrays to identify genes regulated by HCF-1 in a daf-16-dependent manner. Samples from young adult worms were hybridized to Agilent microarrays to identify genes differentially expressed in hcf-1(pk924)/daf-16(mgDf47);hcf-1(pk924) and compared to hcf-1(pk924)/N2 arrays.
ORGANISM(S): Caenorhabditis elegans 
2011-07-22 | E-GEOD-30725 | biostudies-arrayexpress
TranscriptomicsExpression changes in HeLa cells treated with siRNA against HCFC1 or control luciferase
We compared in triplicate mRNA levels from cells treated with siRNA against either HCF-1 or, as a negative control, luciferase. We observed that 19% of Refseq annotated genes are differentially expressed (either up or down regulated with a multiple testing corrected p value of M-bM-^IM-$ 0.05) upon...
ORGANISM(S): Homo sapiens 
2012-07-30 | E-GEOD-31412 | biostudies-arrayexpress
GenomicsGenome wide binding sites of BAP1, HCF1 and OGT
We report the genome wide binding sites of BAP1, HCF1 and OGT in bone marrow derived macrophages. De-ubiquitinating enzyme BAP1 is mutated in a hereditary cancer syndrome with increased risk of mesothelioma and uveal melanoma. Somatic BAP1 mutations occur in various malignancies. We show that mouse ...
ORGANISM(S): Mus musculus 
2012-11-07 | E-GEOD-40723 | biostudies-arrayexpress
ProteomicsIdentify binding proteins of HCF-1 by IP-MS in C. elegans
We tagged HCF-1 with a GFP protein. We then identified the binding proteins of HCF-1 by IP-MS.
ORGANISM(S): Caenorhabditis Elegans 
2024-01-24 | PXD047247 | JPOST Repository
ProteomicsThe chromatin factors SET-26 and HCF-1 oppose the histone deacetylase HDA-1 in longevity and gene regulation in C. elegans
In this study, a GFP-tagged version of the protein HCF-1 was immuno-precipitated from C. elegans lysates of the strain IU171 and co-purifying proteins were identified by LC-MS/MS. As a negative control, the same immuno-precipitation was conducted from wild-type (strain N2) worms that did not carry a...
ORGANISM(S): Caenorhabditis elegans 
2024-01-29 | PXD047509 | Pride
Lc-msms C. elegans Immuno precipitation 
TranscriptomicsOcular fibroblast types differ in their mRNA profiles - implications for fibrosis prevention after aqueous shunt implantation
Surgical glaucoma therapy is characterized by implantation of an aqueous shunt either draining into the extraocular Tenon’s space or the intraocular suprachoroidal space. In both cases the long term drainage is hampered by fibrotic reactions around the outflow region of the shunt. The prevention of ...
ORGANISM(S): Homo sapiens 
2012-09-25 | E-GEOD-40929 | biostudies-arrayexpress
Transcriptomicshcf-1(-) transcriptional profiling
We used microarrays to identify genes regulated by HCF-1 in a daf-16-dependent manner.
ORGANISM(S): Caenorhabditis elegans 
2011-07-23 | GSE30725 | GEO
GenomicsThe epigenetic cell-cycle regulator HCF-1 is recruited to active CpG island-containing promoters together with the ZNF143, THAP11(Ronin), YY-1 and GABP transcription factors.
This SuperSeries is composed of the following subset Series: GSE31412: Expression changes in HeLa cells treated with siRNA against HCFC1 or control luciferase GSE31417: Genome-wide study of HCFC1 binding sites and its associated transcription factors in cycling Human HeLa cells Refer to individual S...
ORGANISM(S): Homo sapiens 
2012-07-30 | E-GEOD-31419 | biostudies-arrayexpress
GenomicsHCF-1:OGT-mediated transcriptional repression of WDR91 coordinates neuronal differentiation and CNS regeneration
HCF-1:OGT-mediated transcriptional repression of WDR91 coordinates neuronal differentiation and CNS regeneration
PRJEB123589 | ENA
GenomicsHCF-1:OGT-mediated transcriptional repression of WDR91 coordinates neuronal differentiation and CNS regeneration
HCF-1:OGT-mediated transcriptional repression of WDR91 coordinates neuronal differentiation and CNS regeneration
PRJEB123590 | ENA
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