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MetabolomicsMetabolomics reveals impaired maturation of HDL particles in adolescents with hyperinsulinaemic androgen excess
Hyperinsulinaemic androgen excess (HIAE) in prepubertal and pubertal girls usually precedes a broader pathological phenotype in adulthood that is associated with anovulatory infertility, metabolic syndrome and type 2 diabetes. The metabolic derangements that determine these long-term health risks re...
2015-04-09 | MTBLS103 | MetaboLights
ProteomicsHuman HDL 2D-LC-MS/MS
Besides modulation of reverse cholesterol transport, high density lipoprotein (HDL) is able to modulate vascular function by stimulating endothelial nitric oxide synthase. Recently, it could be documented that this function of HDL was significantly impaired in patients with chronic heart failure (CH...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080857 | MassIVE
ProteomicsHDL proteome across 93 mouse strains
High-density lipoproteins (HDL) are nanoparticles with >80 associated proteins, phospholipids, cholesterol and cholesteryl esters. We have identified and quantified the ultracentrifugation isolated HDL proteome across 93 strains of mice, a diverse inbred strains of mice, Hybrid Mouse Diversity Panel...
ORGANISM(S): Mus musculus (Mouse) 
2019-04-24 | PXD009473 | Pride
Hdl Strains Mouse 
ProteomicsHuman HDL 2D-LC-MS/MS - Proteome profiles of HDL particles of patients with chronic heart failure are associated with immune response and also include bacteria proteins
Besides modulation of reverse cholesterol transport, high density lipoprotein (HDL) is able to modulate vascular function by stimulating endothelial nitric oxide synthase. Recently, it could be documented that this function of HDL was significantly impaired in patients with chronic heart failure (CH...
ORGANISM(S): Homo sapiens (Human) 
2016-01-04 | PXD002977 | Pride
Hdl variability  hdl functionality lc-ms/ms Human hdl 
ProteomicsProteomic analysis of HDL isolates reveals method-driven variability between ultracentrifugation and immunoaffinity chromatography: an interlaboratory approach
Therefore, the aim of our study is to systematically compare the effect of two different methods of HDL isolation, namely UC and IAC, performed in two independent research laboratories. For this purpose, we used the same plasma pool and protocols optimized to evaluate the influence of those variable...
ORGANISM(S): Homo sapiens (Human) 
2026-01-23 | PXD066558 | Pride
High-density lipoprotein  proteomics  ultracentrifugation  immunoaffinity  quantitative proteomics 
UnknownProteomic analysis of HDL isolates reveals method-driven variability: An interlaboratory approach.
Not available
S-EPMC12803808 | biostudies-literature
UnknownCombined Impact of Mean and Variability of Non-HDL Cholesterol on Myocardial Infarction in Hemodialysis Patients.
Not available
S-EPMC12787241 | biostudies-literature
UnknownJoint effect of visit-to-visit variability in LDL-cholesterol, HDL-cholesterol and HbA1c on cardiovascular and total mortality in patients with diabetes.
Not available
S-EPMC9487118 | biostudies-literature
UnknownA common CNR1 (cannabinoid receptor 1) haplotype attenuates the decrease in HDL cholesterol that typically accompanies weight gain.
Not available
S-EPMC3013130 | biostudies-literature
UnknownTriglyceride to high-density lipoprotein cholesterol ratio variability and incident diabetes: A 7-year prospective study in a Chinese population.
Not available
S-EPMC8504899 | biostudies-literature
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