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Panicum virgatum HDR Resequencing genome sequencing
The cells harvested for microarray analysis were high-dose rate (HDR) irradiated, low-dose rate (LDR) irradiated or unirradiated T-47D cells. The HDR-irradiated cells were harvested 24h after a dose of 0.3 Gy at 35 Gy/h, a time where hyper-radiosensitivity (HRS) had returned. The HRS-deficient LDR-i...
ORGANISM(S): Homo sapiens 
Alternative lengthening of telomeres (ALT) is a homology-directed repair (HDR) mechanism of telomere elongation that controls proliferation in subsets of highly aggressive cancer. Recent studies have revealed that TERRA (telomere repeat-containing RNA) acts to initiate ALT-associated HDR (ALT-HDR). ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD035943 | Pride
HDR-CRISPR promotes targeted genome editing with reduced mutational burden in primary human cells [Amp-seq]
HDR-CRISPR promotes targeted genome editing with reduced mutational burden in primary human cells [CAST-seq]
We have established a technology to endorse DSB resolution via HDR with the goal of facilitating clinical transition of HDR-based editing strategies and increase safety. We have used high throughput sequencing as deposited here to assess safety of our platform
ORGANISM(S): Homo sapiens 
2023-08-11 | GSE225450 | GEO
We have established a technology to endorse DSB resolution via HDR with the goal of facilitating clinical transition of HDR-based editing strategies and increase safety. We have used high throughput sequencing as deposited here to assess safety of our platform
ORGANISM(S): Homo sapiens 
2023-08-11 | GSE225449 | GEO
Genomics
somatic HDR time-course
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