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ProteomicsRAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA
Alternative lengthening of telomeres (ALT) is a homology-directed repair (HDR) mechanism of telomere elongation that controls proliferation in subsets of highly aggressive cancer. Recent studies have revealed that TERRA (telomere repeat-containing RNA) acts to initiate ALT-associated HDR (ALT-HDR). ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD035943 | Pride
Cancer Alt Terra Homology-directed repair Chromatin Transcription Telomere Rad51ap1 
GenomicsRAD51AP1 associated with RNA in HEK293T cells
RAD51AP1 associated with RNA in HEK293T cells
PRJNA1060709 | ENA
TranscriptomicsRAD51AP1 associated with RNA in HEK293T cells
RNAs have versatile roles in DNA damage repair. We here report RAD51AP1 associated with RNAs by PAR-CLIP.
ORGANISM(S): Homo sapiens 
2024-03-11 | GSE252475 | GEO
UnknownPhosphoregulation of RAD51AP1 function in homology-directed repair.
Not available
S-EPMC12439919 | biostudies-literature
UnknownRAD51AP1 is a versatile RAD51 modulator.
Not available
S-EPMC12704761 | biostudies-literature
UnknownRAD51AP1 mediates RAD51 activity through nucleosome interaction.
Not available
S-EPMC8233230 | biostudies-literature
UnknownRAD51AP1-deficiency in vertebrate cells impairs DNA replication.
Not available
S-EPMC4254361 | biostudies-literature
UnknownPre-rRNA facilitates the recruitment of RAD51AP1 to DNA double-strand breaks.
Not available
S-EPMC10959706 | biostudies-literature
UnknownRAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA.
Not available
S-EPMC9713952 | biostudies-literature
UnknownRAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres.
Not available
S-EPMC6778027 | biostudies-literature
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