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TranscriptomicsFunctional characterization of the TERRA transcriptome at damaged telomeres
We characterize the TERRA transcriptome at normal and TRF2-depleted telomeres by RNA-seq and we demonstrate that TERRA upregulation is occurring at all transcribed telomeres upon depletion of TRF2. RNA-sequencing of HeLa mRNA, 4 samples: with or without TERRA enrichment by IP (respectively "IP&...
ORGANISM(S): Homo sapiens 
2014-10-31 | E-GEOD-56727 | biostudies-arrayexpress
GenomicsTerra
Terra Raw sequence reads
PRJNA1054667 | ENA
ProteomicsRAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA
Alternative lengthening of telomeres (ALT) is a homology-directed repair (HDR) mechanism of telomere elongation that controls proliferation in subsets of highly aggressive cancer. Recent studies have revealed that TERRA (telomere repeat-containing RNA) acts to initiate ALT-associated HDR (ALT-HDR). ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD035943 | Pride
Cancer Alt Terra Homology-directed repair Chromatin Transcription Telomere Rad51ap1 
ProteomicsBRCA1 maintains telomere integrity through suppression of TERRA RNA and TERRA R-loop-induced DNA damage
Data in support of Vohhodina et al. "BRCA1 maintains telomere integrity through suppression of TERRA RNA and TERRA R-loop-induced DNA damage"
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-04-21 | MSV000087276 | MassIVE
GenomicsilIthTerr
Ithomia terra
PRJEB87544 | ENA
GenomicsTerra
Terra Metagenome
PRJNA956695 | ENA
ProteomicsTERRA interactome in human ALT cancer cells identified by iDRiP-MS method
Alternative Lengthening of Telomeres (ALT) cancer cells are a subset of cancers that depend on the homologous recombination mechanism to extend their telomere length independent of telomerase. ALT cells contain elevated levels of the telomeric-repeat containing long noncoding RNA (TERRA), which is a...
ORGANISM(S): Homo sapiens (Human) 
2022-09-28 | PXD028882 | Pride
Human Lc-msms Alt U2os Terra Lncrna Idrip-ms 
GenomicsTerra
Terra Raw sequence reads
PRJNA923046 | ENA
GenomicsTerra
Terra Raw sequence reads
PRJNA956134 | ENA
Genomicsterra
terra Raw sequence reads
PRJNA893081 | ENA
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