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ProteomicsPARylation of UBC13 and PDI proteins
NH2OH was used to remove PAR from the PARylated proteins. This treatment left on the PARylated residues a hydroxamic acid derivative, which has a signature mass increase of +15.0109 Da and could be distinguished by mass spectrometry.
ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702) 
2021-07-23 | MSV000087876 | MassIVE
TranscriptomicsExpression data from early diphyodont morphogenesis in minature pig
The miniature pig is diphyodont, making it a valuable alternative model for understanding human tooth development and replacement. However, little is known about gene expression and function during swine odontogenesis. The goal of this study is to undertake the survey of differential gene expressio...
ORGANISM(S): Sus scrofa 
2014-12-23 | E-GEOD-53182 | biostudies-arrayexpress
ProteomicsQuantitative Proteome of Infant Stenotic Ureters Reveals Extracellular Matrix Organization and Oxidative Stress Dysregulation Underlying Ureteropelvic Junction Obstruction
Ureteropelvic junction obstruction (UPJO) is the most frequent cause of congenital hydronephrosis in child. To better investigate the molecular mechanisms of this pathological process, we performed data independent acquisition-based proteomics to compare the stenotic ureter proteome of UPJO in infan...
ORGANISM(S): Homo Sapiens 
2020-08-17 | PXD020116 |
ProteomicsAldehyde dehydrogenase 2 deficiency impairs cell proliferation in alcohol-fed mice
Serum samples from healthy male subjects with active ALDH2*1/*1 (G/G) or healthy male subjects with inactive ALDH2*1*/*2 (G/A) (n=5 per group) recruited from the First Affiliated Hospital of Jilin University (Changchun, China) for measurement of proteomic analysis post one-time acute alcohol drinkin...
ORGANISM(S): Mus Musculus 
PXD065926 |
ProteomicsSS18/BAFs regulate chromatin accessibility dynamics during pluripotent-somatic transition
The exit from pluripotency or pluripotent-somatic transition (PST) landmarks an event of mammalian development, and is also a representative cell-fate transition model, but remains largely unresolved. Recently, we reported construction of robust JUN-induced PST completed in one cell cycle and whose ...
ORGANISM(S): Mus Musculus 
PXD029277 |
ProteomicsSS18 regulates pluripotent-somatic transition through phase separation
The transition from pluripotent to somatic states marks a critical event in mammalian development, but remains largely unresolved. Here we report the identification of SS18 as a regulator for pluripotent to somatic transition or PST by CRISPR-based whole genome screens. Mechanistically, SS18 forms m...
ORGANISM(S): Mus Musculus 
2021-05-23 | PXD026208 |
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