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ProteomicsPhosphoproteomics analysis of TAMs with NEK2 overexpression
NEK2 is considered a key factor in the maintenance of development and function of B cells in multiple myeloma (MM). Importantly, we previously demonstrated that PD-L1 is a substrate of NEK2, and combinatorial inhibition of NEK2 and PD-L1 largely improves the therapeutic efficacy of pancreatic cancer...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-26 | PXD054708 | Pride
Nek2  phosphoproteomics tams  pancreatic cancer 
TranscriptomicsTranscriptional profiling by array to characterize temperature stress responses in larval zebrafish
96 hpf zebrafish larvae were exposed to cold (16 degrees C) or heat (34 degrees C) stress for 2, 12, 24 and 48h. Time-matched controls were maintained at 28 degrees C. The transcriptional responses elicited by temperature stress in larval zebrafish were investigated by microarray.
ORGANISM(S): Danio rerio 
2012-02-01 | E-MTAB-826 | biostudies-arrayexpress
TranscriptomicsTranscriptomic characterization of temperature stress responses in larval zebrafish
96 hpf zebrafish larvae were exposed to cold (16 C) or heat (34 C) stress for 2 and 48h. Time-matched controls were maintained at 28 C. The transcriptional responses elicited by temperature stress in larval zebrafish were investigated by microarray.
ORGANISM(S): Danio rerio 
2012-02-15 | E-MTAB-983 | biostudies-arrayexpress
ProteomicsZebrafish Study Provides Evidence for Porphyromonas gingivalis Outer Membrane Vesicles Eliciting Alzheimer's Disease-Like Pathologies
Periodontitis bacteria release vesicles that can harm the brain. In zebrafish, these vesicles caused brain injury, inflammation, movement problems, and Alzheimer’s-like changes, including amyloid plaques and enzyme activity. This study suggests periodontitis may contribute to Alzheimer’s disease.
ORGANISM(S): Danio Rerio 
2025-08-29 | PXD067862 |
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