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MetabolomicsTen Mouse Organs Proteome and Metabolome Atlas from Adult to Aging

The complexity of the aging process, encompassing numerous organs and systems, poses a significant challenge in identifying and targeting key factors that drive age-related decline. The multi-organ synchronous molecular intricacies underlying natural aging remain elusive. Here we presented a data...

2025-08-29 | MTBLS10642 | MetaboLights
MetabolomicsEstrogen receptor a deficiency in cardiac myocytes reprograms heart-derived extracellular vesicle proteome and induces obesity in female mice (Part 2)
Not available
ORGANISM(S): Mus musculus 
ST002228 | MetabolomicsWorkbench
MetabolomicsEstrogen receptor α deficiency in cardiac myocytes reprograms heart-derived extracellular vesicle proteome and induces obesity in female mice (Part 1)
Not available
ORGANISM(S): Mus musculus 
ST002229 | MetabolomicsWorkbench
MetabolomicsTraining-induced bioenergetic improvement in human skeletal muscle is associated with non-stoichiometric changes in the mitochondrial proteome without reorganisation of respiratory chain content
Not available
ORGANISM(S): Homo sapiens 
ST001907 | MetabolomicsWorkbench
ProteomicsHeart surfaceome profiling using biotin capture
Cell surface proteins (surfaceome) represent key signalling and interaction molecules for therapeutic targeting, biomarker profiling, and cellular phenotyping. Understanding the surfaceome of complex tissues including the heart is essential to investigate membrane composition and function in physiol...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000095912 | MassIVE
ProteomicsHeart extracellular vesicle proteome
Cardiac function is dynamically regulated by intercellular signalling. As an important intercellular signalling mediator, this study focused on isolating and defining membrane bound signalling packages termed extracellular vesicles (EVs) directly from heart. Here, we utilised a gentle, enzymatic per...
ORGANISM(S): Mus musculus (Mouse) 
2021-04-26 | PXD023570 | Pride
Heart Signaling Extracellular vesicles Proteomics 
TranscriptomicsHeart-muscle expression ratios in pig obtained by 454-sequencing, iTRAQ-based proteomics and cDNA microarrays
The recent development within high-throughput technologies for expression profiling has allowed for parallel analysis of transcriptomes and proteomes in biological systems such as comparative analysis of transcript and protein levels of tissue regulated genes. Until now, such studies of have only in...
ORGANISM(S): Sus scrofa 
2009-01-22 | E-GEOD-10122 | biostudies-arrayexpress
ProteomicsExtracellular vesicle proteome from cardiac muscle critical for protection against obesity in female mice
Dysregulation of ER has been linked with increased metabolic and cardiovascular disease risk. Uncovering the impact of ERα deficiency in specific tissues has implications for understanding the role ERα in normal physiology and disease, the increased disease risk in postmenopausal women, and the desi...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-15 | PXD027811 | Pride
Cardiac Heart Extracellular vesicle Tissue Obesity Human Proteome 
ProteomicsHeart-derived extracellular vesicles reprogram smooth muscle cells
Dysregulation of ER has been linked with increased metabolic and cardiovascular disease risk. Uncovering the impact of ERα deficiency in specific tissues has implications for understanding the role of ERα in normal physiology and disease, the increased disease risk in postmenopausal women, and the d...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-15 | PXD033078 | Pride
Heart Extracellular vesicles Proteome Reporgram Muscle 
ProteomicsRegion and cell-type resolved multi-omic altas of the heart
This work presented the panoramic heart proteome map, and served as the rich resource for heart researches in the future.
ORGANISM(S): Homo Sapiens Rattus Norvegicus Mus Musculus 
2025-02-17 | PXD060863 |
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