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MetabolomicsMetabolomics Adaptation of Juvenile Pacific Abalone Haliotis discus hannai to Heat Stress
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ORGANISM(S): Haliotis discus hannai 
ST001324 | MetabolomicsWorkbench
MetabolomicsDecoding heat-shock responses in Vitis vinifera L. by metabolic, VOC and physiological profiling: towards the identification of volatile and metabolic biomarkers

Grapevine (Vitis spp.) is a crop of major economic importance in Europe. Rising temperatures and extreme weather events reduce yield and alter berry composition, affecting wine quality. Despite advances in vineyard management, mechanisms underlying grapevine thermotolerance remain poorly understo...

2026-06-26 | MTBLS13195 | MetaboLights
MetabolomicsGut Microbiota Contributes to Heat Tolerance Through Metabolic Remodeling and Suppression of Thermogenesis in Chickens
Background The gut microbiota is increasingly recognized as a key regulator of host metabolic adaptation to environmental challenges. However, whether breed-specific gut microbiota contributes to variation in heat tolerance among poultry breeds remains unclear. This study used Cyan-shank partridge c...
2026-06-18 | MTBLS14785 | MetaboLights
MetabolomicsExploring the variations in intestinal microbial communities and metabolite profiles between heat-sensitive and heat-tolerant chickens through a comprehensive multi-omics approach

Heat stress (HS) compromises poultry health by disrupting intestinal integrity and microbiota homeostasis. This study compared heat stress-susceptible (HS-SUS) and heat stress-resistant (HS-RES) White Leghorn chickens under chronic cyclic HS (35±2°C, 8 h/day). HS-RES chickens demonstrated superio...

2025-09-12 | MTBLS12991 | MetaboLights
MetabolomicsMetabolomic data of heat stress response in Lavandula angustifolia

Untargeted metabolomic profiling of Lavandula angustifolia under progressive heat stress conditionsate.

2025-08-03 | MTBLS12670 | MetaboLights
MetabolomicsTranscriptome-and metabolome-based mechanisms of high-temperature adaptation in triploid rainbow trout (Oncorhynchus mykiss)

High-temperature stress critically challenges cold-water aquaculture; however, the size-dependent molecular mechanisms underlying thermal adaptation in triploid rainbow trout (Oncorhynchus mykiss) remain poorly understood. Here, we integrated transcriptomic and metabolomic profiling of liver tiss...

2026-05-17 | MTBLS14507 | MetaboLights
MetabolomicsGut Microbiota Orchestrates Thermoregulatory Adaptation in Broilers via a Hypothalamic 5-HT–TRPC4 Pathway

The gut microbiota is being increasingly recognized as a pivotal regulator of thermal adaptation in homeothermic rodents. However, it remains unclear whether similar mechanisms operate in other homeothermic species, such as birds, which exhibit higher basal body temperature and limited heat toler...

2026-01-28 | MTBLS13794 | MetaboLights
TranscriptomicsThe Rpd3L HDAC complex is essential for the heat stress response in yeast
To ensure cell survival and growth during temperature increase, eukaryotic organisms respond with transcriptional activation that results in accumulation of proteins that protect against damage, and facilitate recovery. To define the global cellular adaptation response to heat stress, we performed a...
ORGANISM(S): Saccharomyces cerevisiae 
2010-04-23 | E-GEOD-17514 | biostudies-arrayexpress
TranscriptomicsA model of exposure to extreme environmental heat uncovers the human transcriptome to heat stress
The molecular mechanisms by which individuals subjected to environmental heat stress either adapt or develop heat-related complications are not well understood. We analysed the changes in blood mononuclear gene expression patterns in human volunteers exposed to an extreme heat in a sauna (temperatur...
ORGANISM(S): Homo sapiens 
2017-11-01 | E-MTAB-6212 | biostudies-arrayexpress
TranscriptomicsDifference in gene expression between WT (Col-0) and atxrn4-3 mutant under non-stress and heat stress condition
Arabidopsis 5’-3’ exoribonuclease, AtXRN4, a homolog of yeast Xrn1p, functions in degradation of uncapped RNAs after de-capping step. While Xrn1p-dependent on plant XRN4’s targets for degradation is still limited. For understanding biological function of AtXRN4, we tested survivability of atxrn4 mut...
ORGANISM(S): Arabidopsis thaliana 
2015-07-14 | E-GEOD-66369 | biostudies-arrayexpress
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