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MetabolomicsDecoding heat-shock responses in Vitis vinifera L. by metabolic, VOC and physiological profiling: towards the identification of volatile and metabolic biomarkers

Grapevine (Vitis spp.) is a crop of major economic importance in Europe. Rising temperatures and extreme weather events reduce yield and alter berry composition, affecting wine quality. Despite advances in vineyard management, mechanisms underlying grapevine thermotolerance remain poorly understo...

2026-06-26 | MTBLS13195 | MetaboLights
TranscriptomicsTransriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart.
FBXW7 modulates stress response by post-translational modification of HSF1 HSF1 orchestrates the heat-shock response upon exposure to heat stress and activates a transcriptional program vital for cancer cells. Genes positively regulated by HSF1 show increeased expression during heat shock while thei...
ORGANISM(S): Homo sapiens 
2015-02-20 | E-GEOD-57397 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis Hsa32 mutant and wild type plants subjected to heat shock
Plants and animals share similar mechanisms in the heat-shock (HS) response, such as synthesis of the conserved HS proteins (Hsps). However, because plants are confined to a growing environment, in general they require unique features to cope with heat stress. We have analyzed the function of a nove...
ORGANISM(S): Arabidopsis thaliana 
2007-06-27 | E-GEOD-4062 | biostudies-arrayexpress
TranscriptomicsThe heat shock response of killifish (Fundulus heteroclitus): candidate gene and heterologous microarray approaches.
Subspecies of the Atlantic killifish, Fundulus heteroclitus, differ in their maximum thermal tolerance. To determine whether there is a link between the heat shock response (HSR) and maximum thermal tolerance, we exposed 20ºC acclimated killifish from these subspecies to a 2hr heat shock at 34ºC ...
ORGANISM(S): Fundulus heteroclitus 
2010-06-20 | E-GEOD-18792 | biostudies-arrayexpress
TranscriptomicsSystemic Comparison of Heat Shock Response Induced by Heat Shock and a Proteasome Inhibitor in Mouse Fibrosarcoma Cells and Their Thermotolerant Counterparts
Heat shock response (HSR) is a cellular defense mechanism against various stresses. Both heat shock and proteasome inhibitor MG132 cause the induction of heat shock proteins, a distinct feature of HSR. To better understand the molecular basis of HSR, we subjected the mouse fibrosarcoma cell line, RI...
ORGANISM(S): Mus musculus 
2011-11-09 | E-GEOD-24197 | biostudies-arrayexpress
MetabolomicsUntargeted serum metabolomics of dairy goats under heat stress and melatonin supplementation
Serum untargeted metabolomic profiling was performed to characterize metabolic alterations induced by heat stress and to evaluate the potential protective effects of melatonin supplementation in dairy goats. Serum samples were collected from dairy goats assigned to three experimental groups: a norma...
2026-09-10 | MTBLS15437 | MetaboLights
TranscriptomicsTranscription profiling of Arabidopsis HsfA2 knockout plants response to heat shock
The expression of heat-shock proteins (Hsps) induced by a non-lethal heat treatment confers acquired thermotolerance (AT) to organisms against a subsequent challenge of otherwise lethal temperature. After stress signal lifted, AT gradually decayed with the decline of Hsps during recovery period. The...
ORGANISM(S): Arabidopsis thaliana 
2008-06-13 | E-GEOD-4760 | biostudies-arrayexpress
MetabolomicsMetabolic responses of rice cultivars with different tolerance to combined heat and drought stress under field conditions
Rice is susceptible to both heat and drought stress, in particular during flowering and grain filling, when both grain yield and quality may be severely compromised. However, under field conditions, these two stresses rarely occur separately. Under well-watered conditions, plants avoid heat stress b...
2019-04-25 | MTBLS801 | MetaboLights
TranscriptomicsTranscription profiling of Corynebacterium glutamicum shows a differential response to moderate or severe heat shock of the HrcA- and HspR-dependent systems
Genome-wide transcription profiles analysis of the heat-shocked wild-type strain under moderate (40¡C) and severe heat stress (50¡C) revealed that a large number of genes are differentially expressed after heat shock. 358 genes were up-regulated and 420 were down-regulated in response to moderate he...
ORGANISM(S): Corynebacterium glutamicum 
2008-12-10 | E-MTAB-66 | biostudies-arrayexpress
TranscriptomicsThe Rpd3L HDAC complex is essential for the heat stress response in yeast
To ensure cell survival and growth during temperature increase, eukaryotic organisms respond with transcriptional activation that results in accumulation of proteins that protect against damage, and facilitate recovery. To define the global cellular adaptation response to heat stress, we performed a...
ORGANISM(S): Saccharomyces cerevisiae 
2010-04-23 | E-GEOD-17514 | biostudies-arrayexpress
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