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ProteomicsS. aureus COL anaerobiosis absolute protein quantification
Absolute protein quantification was applied to follow the dynamics of the cytoplasmic proteome of Staphylococcus aureus in response to long-term oxygen starvation. For 1,168 proteins, the majority of all expressed proteins, molecule numbers per cell have been determined to monitor the cellular inves...
ORGANISM(S): Staphylococcus aureus (strain COL) 
2016-07-11 | PXD000330 | Pride
Absolute protein quantification Lc-mse Anaerbiosis Synapt Lc-imse Staphylococcus aureus 
ProteomicsBacillus pumilus exponential phase
Cytoplasmic and membrane proteome of cells growing in minimal and complex media
ORGANISM(S): Bacillus pumilus (strain SAFR-032) 
2015-03-12 | PXD000780 | Pride
Cytoplasmic proteome Bacillus pumilus Membrane proteome 
TranscriptomicsParalogous MarR/DUF24-family repressors YodB and CatR control expression of the catechol dioxygenase CatE in Bacillus subtilis
The redox-sensing MarR/DUF24-type repressor YodB controls expression of the azoreductase AzoR1 and the nitroreductase YodC that are involved in detoxification of quinones and diamide in Bacillus subtilis. In the present paper, we identified YodB and its paralog YvaP (CatR) as repressors of the yfiDE...
ORGANISM(S): Bacillus subtilis 
2010-06-29 | E-GEOD-22603 | biostudies-arrayexpress
TranscriptomicsExpression data of multiple sclerosis patients receiving Interferon-beta therapy
The purpose of this study was to characterize the transcriptional effects induced by subcutaneous IFN-beta-1b treatment (Betaferon, 250 µg every other day) in patients with relapsing-remitting form of multiple sclerosis (MS). By using Affymetrix DNA microarrays, we obtained genome-wide expression pr...
ORGANISM(S): Homo sapiens 
2010-09-29 | E-GEOD-24427 | biostudies-arrayexpress
TranscriptomicsA proteomic view on the cell biology of Staphylococcus aureus proteome
The genome sequence is the “blue-print of life”, but proteomics is required to relate this blue-print of life to the actual physiology of living cells. Because of their low complexity – only about 2.000 proteins make a Staphylococcus aureus cell viable – bacteria are excellent model systems to ident...
ORGANISM(S): Staphylococcus aureus 
2009-11-11 | E-GEOD-15060 | biostudies-arrayexpress
ProteomicsAlterations in Bacillus subtilis caused by high salinity and the compatible solute glycine betaine
Cells were grown aerobically at 37 degC in Spizizen minimal medium either supplemented with 1 mM glycine betaine, 1.2 M NaCl or 1.2 M NaCl and 1 mM glycine betaine. Cells were harvested in the exponential growth phase at an OD600nm of 1.0. Proteome analysis was performed with samples from three biol...
ORGANISM(S): Bacillus Subtilis (ncbitaxon:1423) 
2020-01-08 | MSV000084766 | MassIVE
UnknownDevelopment and psychometric evaluation of an instrument to measure knowledge, skills, and attitudes towards quality improvement in health professions education: The Beliefs, Attitudes, Skills, and Confidence in Quality Improvement (BASiC-QI) Scale.
Not available
S-EPMC6565662 | biostudies-literature
TranscriptomicsTargeted transcriptome analysis of the SigB regulon in Bacillus subtilis
Bacillus subtilis is exposed to a wide range of transitory stress and starvation conditions. Here we investigate the expression changes observed in the B. subtilis wild type strain 168 and its isogenic sigB mutant(BSM29) with respect to each stress condition tested. Gene expression was queried for t...
ORGANISM(S): Bacillus subtilis 
2012-03-14 | E-GEOD-32895 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of the Staphylococcus aureus response to mupirocin
In the present study we analyzed the response of S. aureus to mupirocin, the drug of choice for nasal decolonization of S. aureus. Mupirocin selectively inhibits the bacterial isoleucyl-tRNA synthetase (IleRSs) leading to the accumulation of uncharged isoleucyl-tRNA and hence (p)ppGpp. The latter is...
ORGANISM(S): Staphylococcus aureus 
2012-01-23 | E-GEOD-30743 | biostudies-arrayexpress
TranscriptomicsThe global expression profile of Bacillus subtilis to the toxic carbonyls methylglyoxal (MG) and formaldehyde (FA)
Abstract of associated menuscript; Quinones and alpha,beta-unsaturated carbonyls are naturally occurring electrophiles that target cysteine residues via thiol-(S)-alkylation. We analyzed the global expression profile of Bacillus subtilis to the toxic carbonyls methylglyoxal (MG) and formaldehyde (FA...
ORGANISM(S): Bacillus subtilis 
2010-05-15 | E-GEOD-13925 | biostudies-arrayexpress
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