Sort   by:  
 Page size 
TranscriptomicsReference Genes for MiRNAome Analysis of Urothelial Carcinomas
Background/Objective: Quantitative real-time PCR (RT-qPCR) is widely used in miRNA expression studies on cancer. To compensate for the analytical variability produced by the multiple steps of the method, relative quantification of the measured miRNAs is required, which is based on normalization to e...
ORGANISM(S): Homo sapiens 
2013-02-26 | E-GEOD-36121 | biostudies-arrayexpress
TranscriptomicsImmune response eQTL study in primary human monocytes stimulated with multiple microbial ligands under multiple time points
Gene expression arrays and genotyping data in primary human monocytes from healthy individuals of European ancestry that have either been unstimulated (baseline), exposed to Lipopolysaccharide (90 minutes or 6 hours duration), muramyl-dipeptide (90 minutes or 6 hours duration) or transfected with 5’...
ORGANISM(S): Homo sapiens 
2017-05-16 | E-MTAB-5631 | biostudies-arrayexpress
UnknownRecruiting young pre-symptomatic children for a clinical trial in type 1 diabetes: Insights from the Fr1da insulin intervention study.
Not available
S-EPMC6126533 | biostudies-literature
UnknownCloning and characterization of the Schizosaccharomyces pombe tRNA:pseudouridine synthase Pus1p.
Not available
S-EPMC115158 | biostudies-literature
ProteomicsDegron flexibility enforces auxin sensing
Cullin RING-type E3 ubiquitin ligase SCFTIR1/AFB1-5 and their ubiquitylation targets, AUX/IAAs, sense auxin concentrations in the nucleus. TIR1 binds a surface- exposed degron in AUX/IAAs promoting their ubiquitylation and rapid auxin-regulated proteasomal degradation. Here, we resolved TIR1·auxin·I...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2020-05-27 | PXD015392 | Pride
Degron Auxin Phytohormones Aux/iaa Scftir1 Intrinsic disorder Allostery 
TranscriptomicsGenome-wide analysis of gene expression patterns in human kidney cancer [patients without metastasis]
To investigate the mechanisms of ccRCC progression and metastasis, we performed expression profiling of human kidney cancer and benign tissues. mRNA microarray expression analysis was performed by using 28 matched malignant and non-malignant kidney tissue samples from 14 ccRCC patients without diag...
ORGANISM(S): Homo sapiens 
2016-08-31 | E-GEOD-66270 | biostudies-arrayexpress
UnknownRenal Interstitial Platelet-Derived Growth Factor Receptor-β Cells Support Proximal Tubular Regeneration.
Not available
S-EPMC5967761 | biostudies-literature
UnknownNovel [NiFe]- and [FeFe]-hydrogenase gene transcripts indicative of active facultative aerobes and obligate anaerobes in earthworm gut contents.
Not available
S-EPMC3165394 | biostudies-literature
ProteomicsVariation in auxin sensing guides AUX/IAA repressor ubiquitylation and destruction
Auxin is a drug-like small molecule and morphogen that triggers the formation of SCFTIR1/AFB-AUX/IAA co-receptor complexes leading to ubiquitylation and proteasome-dependent degradation of AUX/IAA transcriptional repressors in plants. Here, we systematically dissect auxin sensing by SCFTIR1-IAA6 and...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2017-06-14 | PXD004027 | Pride
Phytohormone Ubiquitylation Auxin Scf-type e3 ligase Ubiquitination Tir1/afbs Proteolysis Aux/iaa 
TranscriptomicsBladder cancer: analysis of miRNA-mRNA interactions
Background: MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression. Their abilyty to affect multiple gene pathways by targeting to various mRNAs makes them to an interesting class of regulators. The interplay between miRNA and mRNA has been proposed as an important process in can...
ORGANISM(S): Homo sapiens 
2013-08-24 | E-GEOD-40355 | biostudies-arrayexpress
Sort   by:  
 Page size