Sort   by:  
 Page size 
TranscriptomicsPorphyromonas gingivalis W50 Heme-excess vs Heme-limitation
Transcription profiling of P. gingivalis W50 grown in continuous culture under conditions of heme-excess and heme-limitation. Reference design (using Cy5 labelled genomic DNA as the reference) to compare two conditions: heme-excess vs heme-limitation. Three samples for each condition, independently...
ORGANISM(S): Porphyromonas gingivalis 
2010-05-16 | E-GEOD-13375 | biostudies-arrayexpress
TranscriptomicsHeme Deficient vs Wild Type in Low Iron
Heme Deficient or Wild Type (normal heme) for 6 hrs with iron chelation by BPS. Single Experiment with Probe Reversal 1. GSM78518 (Cy3) vs GSM78519 (Cy5) 2. GSM78520 (Cy3) vs GSM78521 (Cy5)
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-30 | E-GEOD-3470 | biostudies-arrayexpress
ProteomicsDepletion Assisted Hemin Affinity (DAsHA) Proteomics Reveals an Expanded Landscape of Heme Binding Proteins in the Human Proteome
Heme b (iron protoporphyrin IX) plays important roles in biology as a metallocofactor and signaling molecule. However, the targets of heme signaling and the network of proteins that mediate the exchange of heme from sites of synthesis or uptake to heme dependent or regulated proteins are poorly unde...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD037165 | Pride
Heme Heme trafficking Proteomics Heme binding protein Cell stress Heme affinity Hemin agarose Labile heme pool 
ProteomicsA heme-binding domain in a voltage gated porassium channel
Heme-affinity pull-down assays and proteomics of lysates from primary cortical neurons identified and EAG channel, hERG3 (Kv11.3) binds to heme.
ORGANISM(S): Mus musculus (Mouse) 
2020-09-17 | PXD019887 | Pride
Eag channel Ether-a-go-go Heme Waters q-tof Domain 
ProteomicsThe heme regulatory motifs of heme oxygenase-2 function to transfer heme to the catalytic site for degradation
Heme regulatory motifs (HRMs) are found in a variety of proteins that are involved in diverse biological functions. In the C-terminal tail region of human heme oxygenase-2 (HO2), there are two HRMs whose cysteines form a disulfide bond; when reduced, these cysteines are available to bind Fe3+-heme. ...
ORGANISM(S): Homo sapiens (Human) 
2020-03-18 | PXD017538 | Pride
Enzyme mechanisms  enzyme kinetics  protein dynamics  conformational change  hydrogen deuterium exchange  hdxms 
ProteomicsProfiling the heme-binding proteomes of bacteria using chemical proteomics
Heme is a cofactor with myriad roles and is essential to almost all living organisms. Accordingly, bacte-rial pathogens have developed numerous mechanisms to acquire heme from their hosts. Beyond classi-cal gas transport and catalytic functions, heme is increasingly appreciated as a tightly controll...
ORGANISM(S): Escherichia coli Enterococcus faecalis (Streptococcus faecalis) 
2023-12-05 | PXD036133 | Pride
Cofactor Bacterial pathogens Heme Lc-ms/ms 
ProteomicsStructural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERBβ
Heme is the endogenous ligand for the constitutively repressive REV-ERB nuclear receptors, REV-ERBα (NR1D1) and REV-ERBβ (NR1D2), but how heme regulates REV-ERB activity remains unclear. While cellular studies indicate heme is required for the REV-ERBs to bind the corepressor NCoR and repress transc...
ORGANISM(S): Mus musculus (Mouse) 
2021-02-24 | PXD021761 | Pride
Orphan nuclear receptor Rev-erb Ligand binding Protein-protein interactions 
ProteomicsMalaria parasites require a divergent heme oxygenase for apicoplast biogenesis
Affinity purification data for Heme Oxygenase from Plasmodium falciparum
ORGANISM(S): Plasmodium Falciparum (ncbitaxon:5833) 
2024-05-06 | MSV000094692 | MassIVE
TranscriptomicsPorphyromonas gingivalis 33277 wild-type vs Fur orthologue Har isogenic mutant ECR455
Porphyromonas gingivalis is a major pathogen associated with the microbial biofilm-mediated disease chronic periodontitis. P. gingivalis has an obligate requirement for iron and protoporphyrin IX which it satisfies by transporting heme and iron liberated from the human host. The level of cellular ir...
ORGANISM(S): Porphyromonas gingivalis ATCC 33277 
2015-04-01 | E-GEOD-37099 | biostudies-arrayexpress
UnknownFungal phytochrome chromophore biosynthesis at mitochondria
Not available
S-SCDT-EMBOJ-2021-108083 | biostudies-other
Sort   by:  
 Page size