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ProteomicsNemo-like kinase drives Foxp3 stability and is critical for maintenance of immune tolerance by regulatory T cells
The Foxp3 transcription factor is a crucial determinant of both regulatory T (TREG) cell development and their functional maintenance. Appropriate modulation of tolerogenic immune responses therefore requires tight regulation of Foxp3 transcriptional output, and this involves both transcriptional an...
ORGANISM(S): Mus musculus (Mouse) 
2019-09-02 | PXD011164 | Pride
Nlk Ubiquitination Phosphorylation Foxp3 Nlk Tcr Immune tolerance Regulatory t cell 
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