Sort   by:  
 Page size 
ProteomicsThe critical role of MLKL in hemorrhagic stroke and the therapeutic potential of its associated protein network
MLKL, as the executor of necroptosis and a critical factor in the inflammation, has been shown to be associated with the progression of hemorrhagic stroke. Studies identified MLKL is a promoting factor in this process, suggesting its potential as a therapeutic target to mitigate post-hemorrhagic str...
ORGANISM(S): Mus Musculus 
2024-09-27 | PXD056595 |
GenomicsGenetic and Environmental Risk Factors for Hemorrhagic Stroke study
Genetic and Environmental Risk Factors for Hemorrhagic Stroke study
PRJNA276717 | ENA
ProteomicsiTRAQ-based quantitative serum proteomic analysis in ischemic stroke patients
Hemorrhagic transformation (HT), which occurs with or without reperfusion treatments (thrombolysis and/or thrombectomy), deteriorates the outcomes of ischemic stroke patients. It is essential to find clinically reliable biomarkers that can predict HT. In this study, we screened for potential serum b...
ORGANISM(S): Homo sapiens (Human) 
2021-10-12 | PXD026950 | Pride
Hemorrhagic transformation Itraq Serum proteomics Acute ischemic stroke 
ProteomicsProteome of cerebral thrombi retrieved in acute phase of stroke (ThrombiOMIC)
The proteome of cerebral thrombi from patients recanalized by mechanical thrombectomy in an acute phase of stroke was carried out to determine biomarkers of stroke radio-clinical outcomes for stroke physicians (clinical outcome and mortality at 3 months, intracranial hemorrhagic transformation, etc....
ORGANISM(S): Homo sapiens (Human) 
2024-01-28 | PXD048837 | Pride
Human Lc-msms Thrombus Stroke Proteomics 
GenomicsSingle-Cell RNA-Seq reveals cellualr heterogeneity and gene expression difference between ischemic and hemorrhagic stroke brain
Single-Cell RNA-Seq reveals cellualr heterogeneity and gene expression difference between ischemic and hemorrhagic stroke brain
PRJNA705094 | ENA
ProteomicsIdentification of Stroke Biomarkers Using Proteomic Profiling of Extracellular Vesicles Derived from Human Blood: A Preliminary Study
Stroke is a devastating brain disease that causes extensive neurological impairment and high mortality. Rapid diagnosis and intervention of stroke are necessary to minimize neurological damage and improve recovery. Extracellular vesicles (EVs) have been identified as potential biomarkers for stroke,...
ORGANISM(S): Homo sapiens (Human) 
2025-06-10 | PXD062958 | Pride
Ischemic stroke Extracellular vesicles Hemorrhagic stroke Proteomics. Biomarker 
GenomicsThe National Institute of Neurological Disorders and Stroke (NINDS) Human Genetics Resource Center: DNA and Cell Line Repository (the NINDS Repository): Cerebrovascular Disease/Stroke Study

The National Institute of Neurological Disorders and Stroke (NINDS) Human Genetics Resource Center: DNA and Cell Line Repository (the NINDS Repository), banks phenotypic data and biological samples, including from ...

phs000005.v1.p1 | EGA
ProteomicsINFECTION-DRIVEN PROTEOMIC SIGNATURES IN IMMUNE CELL–DERIVED EXTRACELLULAR VESICLES REFLECT HEMORRHAGIC STROKE OUTCOME
Infectious complications negatively impact outcome of patients with intracerebral hemorrhage (ICH). Identification of biomarkers of the mechanisms by which infection may modify the course of stroke could help predict the clinical evolution, and the search for personalized treatments. Investigating t...
ORGANISM(S): Homo sapiens (Human) 
2026-01-26 | PXD054777 | Pride
Extracellular vesicles Proteomic analysis Infection Hemorrhagic stroke 
GenomicsIschemic Stroke Genetics Study (ISGS)

The third leading cause of death in the United States, stroke is an acute neurological event leading to death of neural tissues. Although the majority of strokes are ischemic strokes, meaning there is oxygen deprivation to the brain, almost 20% of strokes are hemorrhagic, resulting from...

phs000102.v1.p1 | EGA
TranscriptomicsSingle-Cell RNA-Seq reveals cellualr heterogeneity and gene expression difference between ischemic and hemorrhagic stroke brain
Cluster analysis using nonlinear dimensionality reduction ([tSNE]) revealed the differences in global gene expression profiles of healthy and injured striatum, and identified clusters of cells with unique genetic signatures in both ischemic brain and hemorrhagic brain. Genes with p-value < 0.05 and ...
ORGANISM(S): Mus musculus 
2021-10-31 | GSE167593 | GEO
Sort   by:  
 Page size