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UnknownLongitudinal SARS-CoV-2 seroepidemiological investigation among healthcare workers at a tertiary care hospital in Germany.
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S-EPMC8784861 | biostudies-literature
TranscriptomicsHuR differentially regulates unique subsets of mRNAs in estrogen receptor negative and positive breast cancer
Analysis of RNA immunoprecipitation of HuR, a RNA binding protein (RBP), in breast cancer cell lines. This approach, utilizing RNA immunoprecipitation hybridized to microarray (RIP-Chip), provides global identification of putative endogenous mRNA targets of different RBPs. HuR is an RBP that binds ...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-17820 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profiles of primary ER-positive breast tumors following Tamoxifen treatment
Adjuvant tamoxifen is a valid treatment option for women with estrogen receptor (ER)-positive breast cancer. However, up to 40% of patients experience distant or local recurrence or die. MicroRNAs have been suggested to be important prognosticators in breast cancer. This study aims to identify micro...
ORGANISM(S): Homo sapiens 
2014-07-01 | E-GEOD-46823 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human muscle biopsies from Duchenne muscular dystrophy subjects treated with oxandrolone
Three subjects with Duchenne muscular dystrophy (8.3, 10.4, and 16.7 years old) were studied. Baseline studies included stable isotope infusion followed by gastrocnemius muscle biopsy to determine myosin heavy chain synthesis rates. RNA was isolated from the muscle biopsy as well. The subjects were ...
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-1764 | biostudies-arrayexpress
TranscriptomicsIdentification of pathways involved in lung carcinoid progression using gene expression profiling
Identification of differentially expressed genes between pulmonary carcinoid patients with a favorable and a poor disease outcome
ORGANISM(S): Homo sapiens 
2013-03-26 | E-MEXP-3790 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae treated with phenelzine results in a perturbation in the system leads to period doubling
Perturbation of the gated-synchrony system in yeast with phenelzine, an antidepressant drug used in the treatment of affective disorders in humans, leads to a rapid lengthening in the period of the genome-wide transcriptional oscillation. The effect is a concerted, genome-scale change in expression ...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-9302 | biostudies-arrayexpress
TranscriptomicsExpression data for human retinal pigment epithelium (RPE)/choroid - early age-related macular degeneration (AMD) and control samples
Purpose: Age-related degeneration (AMD) is a major cause of blindness in developed countries. The molecular pathogenesis of early events in AMD is poorly understood. We investigated differential gene expression in samples of human retinal pigment epithelium (RPE)/choroid from early AMD and control m...
ORGANISM(S): Homo sapiens 
2013-12-23 | E-GEOD-50195 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of early dendritic cell DC development in hematopoietic progenitor cell line FDCP-mix that is permissive for DC differentiation in the presence of GMCSF
To identify transcription factors that control dendritic cell development, we performed transcriptional profiling analyses of the murine hematopoietic progenitor cell line FDCP-mix that is permissive for DC differentiation in the presence of GMCSF.We reasoned that GM-CSF modulates a defined set of d...
ORGANISM(S): Mus musculus 
2004-08-18 | E-MEXP-151 | biostudies-arrayexpress
TranscriptomicsInfluence of RNA Labeling on Expression Profiling of MicroRNAs
Several technical parameters are now being optimized for microRNA expression profiling experiments, but the finite amount of total RNA available continues to bottleneck clinical investigations. We used microarrays to determine the influence of the labeling reagent on total RNA requirements and data ...
ORGANISM(S): synthetic construct 
2012-05-21 | E-GEOD-30045 | biostudies-arrayexpress
TranscriptomicsUG26-1B6 stroma-derived factors regulate hematopoietic stem cell maintenance
Hematopoietic stem cell (HSC) are regulated by their ’niche’, which limits activation of HSCs, to ensure their maintenance and self-renewal. To dissect the interactions involved during rapid activation in response to stress, we used cell co-culture as a model. Here, we studied gene expression change...
ORGANISM(S): Mus musculus 
2015-09-16 | E-GEOD-68834 | biostudies-arrayexpress
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