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TranscriptomicsTranscription profiling and proteomic profiling of rat colon mucosa from rats fed quercetin
Quercetin has been shown to act as an anti-carcinogen in experimental colorectal cancer (CRC). The aim of the present study was to characterise transcriptome and proteome changes occurring in the distal colon mucosa of rats supplemented with 10 g quercetin/kg diet for 11 weeks. Transcriptome data an...
ORGANISM(S): Rattus norvegicus 
2008-06-15 | E-GEOD-7479 | biostudies-arrayexpress
TranscriptomicsIdentification of genes essential for Moraxella catarrhalis growth under iron-limiting conditions using Genomic Array Footprinting (GAF)
Iron-sequestration by the human host is a first line defense against respiratory pathogens like Moraxella catarrhalis, which consequently experiences a period of iron-starvation during colonization and infection. We determined the genetic requirements for M. catarrhalis growth during iron-starvation...
ORGANISM(S): Moraxella catarrhalis BBH18 
2013-06-06 | E-GEOD-41546 | biostudies-arrayexpress
UnknownMetabolic Disruption Early in Life is Associated With Latent Carcinogenic Activity of Dichloroacetic Acid in Mice.
Not available
S-EPMC6223632 | biostudies-literature
UnknownA double-blind intervention trial in healthy women demonstrates the beneficial impact on Bifidobacterium with low dosages of prebiotic galacto-oligosaccharides.
Not available
S-EPMC11366710 | biostudies-literature
ProteomicsOncogenic Mutations of KRAS Modulate Its Turnover by the CUL3/LZTR1 E3 ligase Complex
KRAS is a proto-oncogene encoding a small GTPase. Mutations contribute up to 30% of human solid tumours including lung adenocarcinoma, pancreatic and colorectal carcinomas. Most KRAS activating mutations interfere with GTP hydrolysis, essential for its role as a molecular switch, leading to alterati...
ORGANISM(S): Homo sapiens (Human) 
2024-03-06 | PXD029725 | Pride
G13d Kras G12d 
ProteomicsThymosin 4 protects against aortic aneurysm via endocytic regulation of growth factor signalling
Vascular stability and tone are maintained by contractile smooth muscle cells (VSMCs). However, injury-induced growth factors stimulate a contractile-synthetic phenotypic modulation which increases susceptibility to abdominal aortic aneurysm (AAA). As a regulator of embryonic VSMC differentiation, w...
ORGANISM(S): Homo sapiens (Human) 
2021-05-21 | PXD024162 | Pride
Smooth muscle cells Lrp1lrp1 Thymosin β4 Vascular stability Endocytosis Abdominal aortic aneurysm Pdgfr)β signalling 
UnknownNewly identified disorder of copper metabolism caused by variants in CTR1, a high-affinity copper transporter.
Not available
S-EPMC9759326 | biostudies-literature
UnknownS1P/S1PR3 signalling axis protects against obesity-induced metabolic dysfunction.
Not available
S-EPMC8803104 | biostudies-literature
UnknownAssessing Error Awareness as a Mediator of the Relationship between Subjective Concerns and Cognitive Performance in Older Adults.
Not available
S-EPMC5104449 | biostudies-literature
UnknownRecent advances in our understanding of the allograft response.
Not available
S-EPMC7946390 | biostudies-literature
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