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ProteomicsThe RNA-binding ubiquitin ligase MKRN1 acts as a sensor for ribosome-associated quality control of poly(A)-translation
Human cells have evolved multiple quality control mechanisms to ensure protein homeostasis by detecting aberrant mRNAs and protein products which are condemned for rapid decay. Translating ribosomes that run into poly(A) tails are terminally stalled, followed by ribosome recycling and rapid decay of...
ORGANISM(S): Homo sapiens (Human) 
2019-08-19 | PXD011772 | Pride
Ubiquitylation Rna binding Ubiquitin remnant profiling Poly(a) Mkrn1 Iclip Ribosome-associated quality control 
MetabolomicsComparative analysis of the adaptation of Staphylococcus aureus to internalization by different types of human non-professional phagocytic host cells (NMR assay)
Staphylococcus aureus is a human pathogen that can cause a wide range of diseases. Although formerly regarded as extracellular pathogen, it has been shown that S. aureus can also be internalized by host cells and persist within these cells. In the present study, we comparatively analyzed survival an...
2015-07-01 | MTBLS102 | MetaboLights
ProteomicsCytosolic proteome of Staphylococcus aureus HG001 post internalization in bronchial epithelial cells - S. aureus dataset
The data set consists of 32 S. aureus cytosolic samples that were collected by GFP supported cell sorting during infection in lung epithelial cells. The data include 8 time points (2.5 h, 6.5 h , 24 h, 48 h, 72 h, and 96 h post infection plus exponential and non-adherent control) that were collected...
ORGANISM(S): Staphylococcus Aureus Hg001 
MSV000082920 | MassIVE
ProteomicsCytosolic proteome of Staphylococcus aureus HG001 post internalization in bronchial epithelial cells - human dataset
The data set consists of 32 cytosolic samples of human bronchial epithelial cells that were collected during infection with S. aureus. The data include 8 (0h, 1h, 2.5 h, 6.5 h, 24 h, 48 h, 72 h, and 96 h post infection) time points that were collected out of four biological replicates. DIA data and ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000082923 | MassIVE
ProteomicsA global Staphylococcus aureus proteome resource applied to the in vivo characterization of host- pathogen interactions
1. DDA dataset used for Staphylococcus aureus HG001 PeptideAtlas build (https://db.systemsbiology.net/sbeams/cgi/PeptideAtlas/buildDetails?atlas_build_id=435) 2. DIA and DDA dataset for the quantitative analyses of the publication (in the update section)
ORGANISM(S): Staphylococcus Aureus Subsp. Aureus Nctc 8325 (ncbitaxon:93061) Homo Sapiens (ncbitaxon:9606) 
2018-06-21 | MSV000082483 | MassIVE
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