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UnknownStructural instability of the prion protein upon M205S/R mutations revealed by molecular dynamics simulations.
Not available
S-EPMC1459491 | biostudies-literature
TranscriptomicsTranscription profiling of human liver cell line after cysteine deprivation
First experiment: Cells were cultured in sulfur amino acid-free DMEM supplemented with 0.1 mM methionine + 0.1 mM cysteine (complete) or supplemented only with 0.1 mM methionine (cysteine-free). Cells were cultured in either medium for 42 h (Long + Cys; Long -Cys) or in cysteine-free medium for 36 ...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9517 | biostudies-arrayexpress
ProteomicsMitochondrial damage drives T-cell immunometabolic paralysis after major surgery
Cytotoxic T cell (CTL) dysfunction is a key feature of immune paralysis following major surgery, significantly increasing the risk of severe nosocomial infections and contributing to elevated mortality in critically ill patients. The pathomechanisms of CTL dysfunction remain unclear. We report that ...
ORGANISM(S): Homo sapiens (Human) 
2025-12-09 | PXD060723 | Pride
TranscriptomicsTranscription profiling by array of human HepG2/C3A cells cultured in complete or leucine-devoid medium
HepG2/C3A cells cultured for 42 h in complete or leucine-devoid medium Experiment Overall Design: Total of 6 Samples (Leu vs noLeu)
ORGANISM(S): Homo sapiens 
2008-11-15 | E-GEOD-13142 | biostudies-arrayexpress
UnknownBacterial urinary tract infection and subclinical bacteriuria in dogs receiving antineoplastic chemotherapy.
Not available
S-EPMC9151473 | biostudies-literature
UnknownDesigning giant Hall response in layered topological semimetals.
Not available
S-EPMC11584889 | biostudies-literature
UnknownA Functional Network Driven by MicroRNA-125a Regulates Monocyte Trafficking in Acute Inflammation.
Not available
S-EPMC9503790 | biostudies-literature
ProteomicsKetogenic diet versus standard high-carbohydrate nutrition in sepsis: a randomized controlled trial
Rationale: Sepsis patients suffer from severe metabolic and immunologic dysfunction that may be amplified by standard carbohydrate-based nutritional regimes. We therefore hypothesize that a ketogenic diet improves sepsis treatment. Objectives: We investigated the safety and feasibility of a ketogeni...
ORGANISM(S): Homo sapiens (Human) 
2024-06-13 | PXD046061 | Pride
Nutritional medicine Inflammation Sepsis Intensive care Critically ill patients Ketogenic diet 
ProteomicsN-terminomics on WT and CASP2 KO mouse hearts
To identify putative substrates processed by Caspase-2 in response to PIDDosome activation in cardiomyocytes, we performed N-terminomics by TMT10-TAILS on P7 hearts isolated from XMLC2-Casp2fl/fl and XMLC2+Casp2fl/fl mice.
ORGANISM(S): Mus musculus (Mouse) 
2026-01-15 | PXD060421 | Pride
Tmt-tails Caspase 2 Heart developement N-terminomics 
ProteomicsEndothelial Glycocalyx Injury in Obstructive Sleep Apnea Links Repetitive Hypoxemia to Immunothrombotic Endothelial Dysfunction
BACKGROUND: Obstructive sleep apnea (OSA) is associated with cardiovascular disease. The endothelial glycocalyx (eGCX) is a shear-sensitive, interfacial barrier towards the intravascular compartment. The relevance of OSA and intermittent hypoxia (IH) for eGCX injury and, subsequently, cardiovascular...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD073409 | Pride
Plasma proteomics Neat plasma 
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