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ProteomicsHNF4G and FOXA1 are context-specific drivers of pancreatic cancer progression
Despite recent advances in the treatment of pancreatic adenocarcinoma (PDAC), clinical outcome remains poor. Previous evidence linked the pioneer transcription factor FOXA1 as a mediator of new regulatory elements that drive tumour progression in models of late-stage disease. Given the critical role...
ORGANISM(S): Homo sapiens (Human) 
2025-08-13 | PXD045980 | Pride
Foxa1 Pancreatic adenocarcinoma Hnf4g Rime 
UnknownHNF4G accelerates glioma progression by facilitating NRP1 transcription.
Not available
S-EPMC9932018 | biostudies-literature
GenomicsBRD4 ChIP-Seq in 22Rv1 cells exogenously expressing HNF4G or GFP
BRD4 ChIP-Seq in 22Rv1 cells exogenously expressing HNF4G or GFP
PRJNA1072116 | ENA
UnknownExpression of HNF4G and its potential functions in lung cancer.
Not available
S-EPMC5915054 | biostudies-literature
UnknownHNF4G increases cisplatin resistance in lung adenocarcinoma via the MAPK6/Akt pathway.
Not available
S-EPMC10010171 | biostudies-literature
GenomicsHNF4G and FOXA1 are context-specific drivers of pancreatic cancer progression [RNA-seq]
HNF4G and FOXA1 are context-specific drivers of pancreatic cancer progression [RNA-seq]
PRJNA1029636 | ENA
GenomicsHNF4G, AR, FOXA1, H3K4me1, H3K27acetyl binding sites upon knockdown and overexpression of HNF4G in 22Rv1 and LNCaP prostate cancer cells respectively
HNF4G is a gastrointestinal tissue enriched master transcriptional regulator seen overexpressed in a subset of prostate cancer. Here we have mapped binding sites of HNF4G, AR, Foxa1, H3K4me1, H3K27acetyl upon knockdown and overexpression of HNF4G in in 22Rv1 and LNCaP cells respectively
ORGANISM(S): Homo sapiens 
2017-11-01 | GSE85558 | GEO
UnknownMetformin inhibits pancreatic cancer metastasis caused by SMAD4 deficiency and consequent HNF4G upregulation.
Not available
S-EPMC7862466 | biostudies-literature
GenomicsHNF4G and FOXA1 are context-specific drivers of pancreatic cancer progression [ChIP-seq]
HNF4G and FOXA1 are context-specific drivers of pancreatic cancer progression [ChIP-seq]
PRJNA1029639 | ENA
GenomicsHNF4G and FOXA1 are context-specific drivers of pancreatic cancer progression [ATAC-seq]
HNF4G and FOXA1 are context-specific drivers of pancreatic cancer progression [ATAC-seq]
PRJNA1029640 | ENA
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