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Ewing sarcoma is a highly aggressive tumor characterized by a translocation between members of the FET family of RNA binding proteins and one of several ETS transcription factors, with the most common translocation being EWS-FLI1. EWS-FLI1 leads to changes in gene expression through mechanisms that ...
ORGANISM(S): Homo sapiens 
The nucleolus is the membraneless organelle in the nucleus mainly responsible for ribosome biogenesis. It is also an excellent stress sensor and any changes on its architecture or composition leads to nucleolar stress deriving in cell cycle arrest and interruption of ribosomal activity. However, nuc...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-04 | PXD046699 | Pride
In this research, we have used a global analysis of TMT-based quantitative proteome coupled with phosphopeptide-enrichment strategies to reveal the mouse testes proteome and find the PTMs associated with the RNA binding protein hnRNPK using Hnrnpk conditional knockout mouse and WT mouse testes.
ORGANISM(S): Mus Musculus 
RNA binding of CBFB and hnRNPK
Effect of overexpressing HNRNPK in glioblastoma stem cell
Hnrnpk orchestrates embryonic growth plate development via regulating glycolysis
RIP-seq for hnRNPK in Min6 cells
Next Generation Sequencing Analysis of Wild Type and hnRNPK-MKO liver transcription
Molecular analyses—including RNA immunoprecipitation, pull-down assays, mass spectrometry, and chromatin immunoprecipitation sequencing—demonstrated that RSDR and hnRNPK stabilize each other, forming a positive feedback loop that amplifies DHODH expression.
ORGANISM(S): Mus Musculus 
2025-03-19 | PXD062047 |
TFAP2C and HNRNPK control cellular bioenergetic metabolism and prion propagation [RNA-seq]
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