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Unknownα-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.
Not available
S-EPMC3346117 | biostudies-literature
ProteomicsUncovering biological heterogeneity in endometrial carcinoma molecular subtypes by proteomic analysis
While endometrial cancer (EC) has an overall favorable prognosis, some patients do poorly and may benefit from refinements of current classification systems. Molecular classification stratifies ECs into four prognostic groups: POLEmut, MMRd (mismatch repair deficient), p53abn, and NSMP (no specific ...
ORGANISM(S): Homo sapiens (Human) 
2025-10-06 | PXD057700 | Pride
Ffpe Endometrial carcinoma Tmt 
ProteomicsWhole proteome analysis of mesonephric-derived cancers describes new potential biomarkers
Mesonephric carcinomas (ME) and Female Adnexal Tumors of probable Wolffian Origin (FATWO) are thought to derive from remnants of the Wolffian/mesonephric ducts – anlages of the male reproductive tract. Mesonephric-like carcinomas (MLC) show identical morphology to ME of the cervix, but occur in the ...
ORGANISM(S): Homo sapiens (Human) 
2020-11-02 | PXD020879 | Pride
Tmt Mesonephric 
UnknownNanopore direct RNA sequencing of human transcriptomes reveals the complexity of mRNA modifications and crosstalk between regulatory features.
Not available
S-EPMC12230237 | biostudies-literature
ProteomicsChanges in the tumor microenvironment mark transition from serous borderline tumor to low grade serous carcinoma
Low grade serous ovarian cancer (LGSC) is a rare subtype of ovarian cancer, characterized by a slow growth rate, resistance to current treatment regimens, multiple recurrences and poor survival. LGSC arise from serous borderline tumor (SBT), however the mechanism of transformation is poorly understo...
ORGANISM(S): Homo sapiens (Human) 
2024-08-15 | PXD046360 | Pride
Tmt Ovarian cancer Serous borderline tumor 
ProteomicsThe proteome of clear cell ovarian carcinoma
Clear cell ovarian carcinoma (CCOC) is the second most common subtype of epithelial ovarian carcinoma. Late stage CCOC is not responsive to gold-standard chemotherapy and result in suboptimal outcome for patients. In-depth molecular insight is urgently needed to stratify the disease and drive therap...
ORGANISM(S): Homo sapiens (Human) 
2022-09-02 | PXD032355 | Pride
Ovarian carcinoma Tmt Clear cell 
UnknownCross-feeding between intestinal pathobionts promotes their overgrowth during undernutrition.
Not available
S-EPMC8617199 | biostudies-literature
UnknownAdult precision medicine: learning from the past to enhance the future.
Not available
S-EPMC7846182 | biostudies-literature
ProteomicsCrithidia fasciculata swimmers vs adherent cells
Comparison of whole cell lystates of swimming (motile) and adherent (stationary) Crithidia fasciculata. Cf-C1 strain parasites grown in standard Brain-Heart Infusion medium supplemented with Hemin and cultured at 28 ºC.
ORGANISM(S): Crithidia fasciculata 
2024-08-23 | PXD055056 | Pride
Crithidia fasciculata Label-free quantitation Lc-msms Kinetoplastid 
UnknownIron(III)-salophene catalyzes redox cycles that induce phospholipid peroxidation and deplete cancer cells of ferroptosis-protecting cofactors.
Not available
S-EPMC11263665 | biostudies-literature
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