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Obesity results from a chronic imbalance between energy intake and energy expenditure, with excess calories stored as fat. As such, weight loss has long been considered as a primary goal of treatment for obesity. A surgical treatment of severe obesity such as gastric bypass provides the most dramati...
ORGANISM(S): Homo sapiens 
Summary: Genetic disorders of muscle cause muscular dystrophy, and are some of the most common inborn errors of metabolism. Muscle also rapidly remodels in response to training and innervation. Muscle weakness and wasting is important in such conditions as aging, critical care medicine, space flig...
ORGANISM(S): Homo sapiens 
Our objective is to describe variations in expression profiles of transcriptional factors during endosperm development, especially during filling phase in which storage proteins are synthesized. Plants from cv. Recital were cultivated under controled conditions. Two biological repetitions were av...
ORGANISM(S): Triticum aestivum 
Dominant pathogenic alleles in tyrosyl-tRNA synthetase (YARS1) are associated with Charcot–Marie–Tooth disease (CMT), a progressive peripheral neuropathy for which no disease-modifying therapies currently exist. While recent advances in amino acid supplementation therapies suggest potential benefit ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-09-14 | PXD078702 | Pride
Objective: Adipose tissue plays a key role in obesity related metabolic dysfunction. MicroRNA (miRNA) are gene regulatory molecules involved in inter-cellular and inter-organ communication. We hypothesised that miRNA levels in adipose tissue would change after gastric bypass surgery and that this wo...
ORGANISM(S): Homo sapiens 
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