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ProteomicsAnalysis of the nuclear proteome fraction of rAAV2-plasmid transfected HEK-293 cells during AAV production
In this comparative proteomic analysis, we focused on proteins in the nuclear fraction. As the nucleus is the epicenter of DNA uptake, transcription, capsid assembly and packaging. Three HEK-293 cell samples i) not transfected, ii) MOCK plasmid transfected, and iii) triple-transfected with rAAV2-pro...
ORGANISM(S): Homo sapiens (Human) 
2025-07-21 | PXD062079 | Pride
Ms/ms Nuclear fraction Fasp Raav production 
ProteomicsPhospho and expression proteomics in chinese hamster ovary cells
We investigated CHO signaling events in a comparative expression and phospho proteomics approach of recombinant mAb producing XL99 cell line and according parental cells. First, on proteomic level differences between producer and parental cells were evaluated by label-free quantification of proteins...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2020-02-26 | PXD010537 | Pride
Phosphoproteomics Cho Silac Lfq Proteomics Lc-msms 
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