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MetabolomicsClock regulation of metabolites reveals coupling between transcription and metabolism
The circadian clock is intricately connected with metabolism, however the precise details of these connections are incomplete. Here we used high temporal resolution metabolite profiling to determine circadian regulation of mouse liver and cell autonomous metabolism. In mouse liver, we found ~50% of ...
2017-04-05 | MTBLS292 | MetaboLights
UnknownA gene atlas of the mouse and human protein-encoding transcriptomes.
Not available
S-EPMC395923 | biostudies-literature
UnknownA functional map of NFkappaB signaling identifies novel modulators and multiple system controls.
Not available
S-EPMC2394752 | biostudies-literature
TranscriptomicsCircadian liver_wt and Clock mutants
One hundred ninety wildtype male C57BL/6J mice age 7-10 weeks were purchased from Jackson Laboratory and entrained to a 12:12 light:dark cycle for 2 weeks. Mice were placed in light-tight boxes on a 12:12 LD cycle for 4 weeks, then released into constant darkness. Starting 30 hours after entry into ...
ORGANISM(S): Mus musculus 
2010-06-11 | E-GEOD-3748 | biostudies-arrayexpress
UnknownGenome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues.
Not available
S-EPMC555478 | biostudies-literature
TranscriptomicsTranscription profiling of Hep3B cells response hypoxia (1%O2) and cobalt chloride (100 uM) and deferoxamine (100 uM) and Nickel Chloride (100 uM)
Comparison between hypoxia (1%O2) and cobalt chloride (100 uM) and deferoxamine (100 uM) and Nickel Chloride (100 uM) in Hep3B cells (human hepatocellular carcinoma cells)
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-1056 | biostudies-arrayexpress
UnknownA coactivator trap identifies NONO (p54nrb) as a component of the cAMP-signaling pathway.
Not available
S-EPMC2154428 | biostudies-literature
TranscriptomicsLarge-scale analysis of the human transcriptome - Novartis dataset
High-throughput gene expression profiling has become an important tool for investigating transcriptional activity in a variety of biological samples. To date, the vast majority of these experiments have focused on specific biological processes and perturbations. Here, we have generated and analyzed ...
ORGANISM(S): Homo sapiens 
2002-12-06 | E-GEOD-96 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human cell lines and tissues (GNF/Novartis)
The tissue-specific pattern of mRNA expression can indicate important clues about gene function. High-density oligonucleotide arrays offer the opportunity to examine patterns of gene expression on a genome scale. Toward this end, we have designed custom arrays that interrogate the expression of the ...
ORGANISM(S): Homo sapiens 
2011-11-08 | E-AFMX-5 | biostudies-arrayexpress
TranscriptomicsCircadian rhythm in clock mutants
One hundred ninety wildtype male C57BL/6J mice age 7-10 weeks were purchased from Jackson Laboratory and entrained to a 12:12 light:dark cycle for 2 weeks. Mice were placed in light-tight boxes on a 12:12 LD cycle for 4 weeks, then released into constant darkness. Starting 30 hours after entry into ...
ORGANISM(S): Mus musculus 
2010-06-12 | E-GEOD-3751 | biostudies-arrayexpress
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