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UnknownGlycan-binding specificities of anti-ABO(H) antibodies and lectins.
Not available
S-EPMC12857864 | biostudies-literature
GenomicsOncogenic ETS proteins replace activated Ras/MAPK signaling in prostate cells.
Approximately 50% of prostate cancers have chromosomal translocations resulting in the over-expression one of four ETS family transcription factors. However, it is not known why these four four family members are selected for oncogenic roles, while other ETS proteins are not. We found that the four...
ORGANISM(S): Homo sapiens 
2011-10-19 | E-GEOD-29808 | biostudies-arrayexpress
TranscriptomicsOncogenic ETS proteins regulate a Ras/MAPK gene expression program in the absence of MAPK signaling
Approximately 50% of prostate cancers have chromosomal translocations resulting in the over-expression one of four ETS family transcription factors. However, it is not known why these four four family members are selected for oncogenic roles, while other ETS proteins are not. We found that the four...
ORGANISM(S): Homo sapiens 
2011-10-18 | E-GEOD-29438 | biostudies-arrayexpress
TranscriptomicsETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells (RNA-Seq)
ETS1 and RAS/ERK regulate a common gene expression program in establishing enviroment suitable for prostate cancer cell migration. mRNA profiles of luciferase knockdown (WT), ETS1 knockdown, and U0126 treated DU145 cells were generated using deep sequencing, in triplicate, using Illumina HiSeq. Knoc...
ORGANISM(S): Homo sapiens 
2014-10-07 | E-GEOD-59020 | biostudies-arrayexpress
UnknownComprehensive analysis of platelet glycoprotein Ibα ectodomain glycosylation.
Not available
S-EPMC10065957 | biostudies-literature
TranscriptomicsChromatin-associated protein kinase C-0 regulates an inducible gene expression program and microRNAs in human T lymphocytes
Studies in yeast have demonstrated that signalling kinases with well known cytoplasmic functions have a surprisingly active role in the nucleus, where they are tethered to chromatin and modulate gene expression programs. Here we provide evidence for a novel function of the signal transduction kinase...
ORGANISM(S): Homo sapiens 
2010-12-14 | E-GEOD-26035 | biostudies-arrayexpress
GenomicsETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells (ChIP-Seq)
ETS1 and RAS/ERK regulate a common gene expression program in establishing enviroment suitable for prostate cancer cell migration. ChIP-sequencing of various transcription factors
ORGANISM(S): Homo sapiens 
2014-10-07 | E-GEOD-59021 | biostudies-arrayexpress
TranscriptomicsERK signaling regulates opposing functions of JUN family transcription factors in prostate cancer cell migration
Knockdowns of c-JUN and JUND had opposite effects on PC3 prostate cell migration. We predicted that c-JUN and JUND control the same set of cell migration genes, but in opposite directions. To test this hypothesis, mRNA with expression changes in c-JUN and JUND knockdown PC3 cell lines were compared ...
ORGANISM(S): Homo sapiens 
2014-10-23 | E-GEOD-53470 | biostudies-arrayexpress
ProteomicsComprehensive analysis of platelet glycoprotein Ibα glycosylation.
Background: Platelet glycoprotein (GP) Ibα is the major ligand-binding subunit of the GPIb-IX-V complex that binds von Willebrand Factor (VWF). GPIbα is heavily glycosylated, and its glycans have been proposed to play key roles in platelet clearance, VWF binding, and as target antigens in immune thr...
ORGANISM(S): Homo sapiens (Human) 
2023-02-09 | PXD035030 | Pride
Human Platelets Glycoproteins 
UnknownAndrogen signaling connects short isoform production to breakpoint formation at Ewing sarcoma breakpoint region 1.
Not available
S-EPMC8364332 | biostudies-literature
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