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MetabolomicsUntargeted metabolomic investigate milk and ruminal fluid of Holstein cows supplemented with Perilla frutescens leaf
Milk compounds are important for human nutrient requirements and health. The ruminal metabolic profile is responsible for dietary nutrition and determines milk production. Perilla frutescens leaf (PFL) is a commonly used medicinal herb due to its bioactive metabolites. This study elucidated the effe...
2020-11-24 | MTBLS2081 | MetaboLights
MetabolomicsEffect of heat stress on serum enzyme activity, antioxidant capacity and immune parameter metabolomics datasets in Holstein cows at different growth stages

Global climate change has led to an increase in release of atmospheric CO2 and average daily temperatures, making heat stress a major challenge in dairy farming. The present study aimed to investigate metabolite changes of Holstein cows at different stages. In this experiment, 10 growing heifers,...

2022-08-11 | MTBLS5148 | MetaboLights
MetabolomicsLactation-related metabolic mechanism investigated based on mammary gland metabolomics and 4 biofluids’ metabolomics relationships in dairy cows

BACKGROUND: Lactation is extremely important for dairy cows; however, the understanding of the underlying metabolic mechanisms is very limited. This study was conducted to investigate the inherent metabolic patterns during lactation using the overall biofluid metabolomics and the...

2018-03-16 | MTBLS411 | MetaboLights
MetabolomicsPlasma metabolome alteration in dairy cows with left displaced abomasum before and after surgical correction
Left displaced abomasum (LDA) leads to substantial changes in the metabolism of dairy cows. Surgical correction of LDA can rapidly improve the health of cows; however, changes in metabolism following surgery are rarely described. To investigate the changes of plasma metabolome in cows with LDA befor...
2022-08-17 | MTBLS4126 | MetaboLights
TranscriptomicsCharacterization and Comparison of the Leukocyte Transcriptomes of Three Cattle Breeds
In this study, we use mRNA-Seq to characterize and compare the leukocyte transcriptomes of Holstein, Jersey, and Cholistani with respect to variations in sequence, expression, and splicing. Poly A+ RNA are extracted from leukocytes of pools of blood drawn from cows of three different breeds, Holstei...
ORGANISM(S): Bos indicus 
2013-07-02 | E-GEOD-48487 | biostudies-arrayexpress
MetabolomicsPlasma metabolite changes in dairy cows during parturition identified using untargeted metabolomics
The metabolic responses of cows undergo substantial changes during the transition from late pregnancy to early lactation. However, the molecular mechanisms associated with these changes in physiological metabolism have not been clearly elucidated. The objective of this study was to investigate metab...
2019-08-20 | MTBLS809 | MetaboLights
MetabolomicsColostrum metabolomic profiling of periparturient dairy cows supplemented with high-dose chromium propionate before calving
This study contains untargeted LC-MS/MS metabolomic profiles of colostrum samples collected at the first milking after calving from Holstein dairy cows in the control and high-dose chromium propionate supplementation groups. Cows received either a basal total mixed ration without supplemental chromi...
2026-09-26 | MTBLS15562 | MetaboLights
MetabolomicsRectal-content metabolomic profiling of periparturient dairy cows supplemented with high-dose chromium propionate before calving
This study contains untargeted LC-MS/MS metabolomic profiles of rectal-content samples collected on the day of calving from Holstein dairy cows in the control and high-dose chromium propionate supplementation groups. Cows received either a basal total mixed ration without supplemental chromium propi...
2026-09-26 | MTBLS15543 | MetaboLights
ProteomicsThe proteomic sequencing results of the colostrum and mature milk from 8 Holstein cows
we performed label-free quantitative proteomics to compare the milk proteomes of colostrum and mature milk in eight healthy primiparous Holstein cows (Bos taurus). Colostrum was collected within 2 h postpartum (group C) and mature milk approximately 15 days after parturition (group M). Proteins were...
ORGANISM(S): Bos taurus (Bovine) 
2026-10-05 | PXD083141 | Pride
Holstein cows Milk 
MetabolomicsRumen-fluid metabolomic profiling of periparturient dairy cows supplemented with high-dose chromium propionate before calving
This study contains untargeted LC-MS/MS metabolomic profiles of rumen-fluid samples collected on the day of calving from Holstein dairy cows in the control and high-dose chromium propionate supplementation groups. Cows received either a basal total mixed ration without supplemental chromium propiona...
2026-09-26 | MTBLS15553 | MetaboLights
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