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TranscriptomicsSex of Blood
Blood samples were taken at 1:00 pm +/- 1 h (Potassium-EDTA-monovettes, Sarstedt, Numbrecht, Germany) to control for circadian influences on gene expression. Blood was taken from normal male controls, normal female controls as well as different patients with disorders of sex development leading to a...
ORGANISM(S): Homo sapiens 
2009-07-13 | E-GEOD-11235 | biostudies-arrayexpress
TranscriptomicsHuman scrotum and labia majora samples treated with DHT and/or AZA
Human scrotum and labia majora samples treated with DHT and/or AZA A compound treatment design type is where the response to administration of a compound or chemical (including biological compounds such as hormones) is assayed. Compound Based Treatment: dihydrotestosterone (DHT), 5-aza-deoxy-cytidin...
ORGANISM(S): Homo sapiens 
2009-05-20 | E-GEOD-11847 | biostudies-arrayexpress
TranscriptomicsFibroblasts from genital and extragenital regions of 46,XY individuals
This dataset contains fibroblasts from different genital and extragenital regions, mostly from 46,XY individuals. Due to proven androgen receptor gene mutations, several individuals have varying degrees of undervirilization of the external genitalia ranging from complete androgen insensitivity syndr...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-6796 | biostudies-arrayexpress
Transcriptomics46,XY sex reversed females with complete androgen insensitivity syndrome
This gene set contains skin fibroblasts from either labia majora of 46,XY sex reversed females having complete androgen insensitivity syndrome due to inactivation mutations of the androgen receptor gene and from the scrotum of normal males. Both, labia majora and scrotum origin from the same embryol...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-6797 | biostudies-arrayexpress
TranscriptomicsBaseline gene transcription in genital fibroblasts
To gain insights into the role of androgen in genital morphogenesis, we compared basal transcriptional patterns in genital fibroblasts from 46,XY individuals with either wild-type AR or germline inactivation of the AR as a result of mutation. A disease state experiment design type is where the state...
ORGANISM(S): Homo sapiens 
2005-12-20 | E-GEOD-3872 | biostudies-arrayexpress
TranscriptomicsAndrogen receptor coregulators
This SuperSeries is composed of the following subset Series: GSE4453: Androgen receptor coregulators baseline comparisons GSE4454: Androgen receptor-coregulators hormone responsiveness LNCaP / GSF Refer to individual Series
ORGANISM(S): Homo sapiens 
2006-10-12 | E-GEOD-4456 | biostudies-arrayexpress
TranscriptomicsAndrogen receptor coregulators baseline comparisons
LNCaP cells are an established androgen receptor expressing prostate carcinoma cell line. Human foreskin fibroblasts also expressing the androgen receptor were obtained from phenotypic normal male individuals. Cells were cultured either at confluency leading to G0 cell cycle state or while they were...
ORGANISM(S): Homo sapiens 
2006-10-12 | E-GEOD-4453 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human genital fibroblasts of normal males and 46,XY females with androgen insensitivity syndrome
Not available
ORGANISM(S): Homo sapiens 
2006-06-06 | E-SMDB-2121 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human genital fibroblasts of normal males and 46,XY females with androgen insensitivity syndrome
Not available
ORGANISM(S): Homo sapiens 
2005-10-13 | E-SMDB-2119 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human androgen receptor expressing prostate carcinoma cell line LNCaP and normal human foreskin fibroblasts expressing the androgen receptor treated with dihydrotestosterone (DHT), ethanol, or untreated vs. a common reference, see E-SMDB-3637
LNCaP cells are an established androgen receptor expressing prostate carcinoma cell line. Human foreskin fibroblasts also expressing the androgen receptor were obtained from phenotypic normal male individuals. Cells were cultured either at confluency leading to G0 cell cycle state or while they were...
ORGANISM(S): Homo sapiens 
2006-11-06 | E-SMDB-3636 | biostudies-arrayexpress
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