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ProteomicsA Pleistocene hominin enamel proteome from Homo antecessor
Hominin relationships and their dispersal throughout Eurasia during the Early and Middle Pleistocene are highly debated. The relationships between Early and Middle Pleistocene hominins, like Homo antecessor and Homo erectus, and hominin species that dominate the Late Pleistocene fossil record, like ...
ORGANISM(S): Homo 
2020-04-02 | PXD014342 | Pride
Enamel Hominins Phosphorylation Palaeoproteomics Lc-ms/ms 
GenomicsHominin-specific NOTCH2NL genes affect Notch signaling and cortical neurogenesis
Hominin-specific NOTCH2NL genes affect Notch signaling and cortical neurogenesis
PRJNA435875 | ENA
TranscriptomicsHominin-specific NOTCH2NL genes affect Notch signaling and cortical neurogenesis
Genetic changes causing brain size expansion in human evolution have remained elusive. Notch signaling is essential for radial glia stem cell proliferation and a determinant of neuronal number in the mammalian cortex. We find three paralogs of human-specific NOTCH2NL are highly expressed in radial g...
ORGANISM(S): Homo sapiens Mus musculus 
2018-02-26 | GSE111082 | GEO
ProteomicsDecontamination enhances palaeoproteomic analysis of a Pleistocene hominin tooth from Khudji, Tajikistan
Contamination is a potential issue in palaeoproteomic studies of human evolution, as it may mask low-abundance endogenous proteins and introduce modern variation into the reconstructed ancient proteome. This contamination may stem from many sources, such as the burial environment, storage facilities...
ORGANISM(S): Homo 
2025-04-24 | PXD050370 | Pride
Decontamination Middle palaeolithic Palaeoproteomics Archaeology Neanderthal 
ProteomicsThe TNH2 hominin enamel proteome
Here we analyse two enamel protein extractions from a Middle Pleistocene hominin from Laos, Asia. The proteome is analyzed for potential phylogenetic information and characterized in terms of its molecular damage and in vivo (serine) phosphorylation.
ORGANISM(S): Homo 
2022-04-06 | PXD018721 | Pride
Enamel Lc-ms/ms Phosphorylation Palaeoproteomics 
GenomicsDe novo enhancer function in divergent hominin haplotypes
De novo enhancer function in divergent hominin haplotypes
PRJNA874114 | ENA
UnknownSporadic sampling, not climatic forcing, drives observed early hominin diversity.
Not available
S-EPMC5948983 | biostudies-literature
GenomicsHominin-specific regulatory elements selectively emerged in oligodendrocytes and are disrupted in autism patients
Hominin-specific regulatory elements selectively emerged in oligodendrocytes and are disrupted in autism patients
PRJNA541855 | ENA
UnknownZanadamu: An African hominin isotopic dataset.
Not available
S-EPMC10493875 | biostudies-literature
UnknownDefining paleoclimatic routes and opportunities for hominin dispersals across Iran.
Not available
S-EPMC9977010 | biostudies-literature
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