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ProteomicsProteomic study of evolved P. aeruginosa strains grown in S. aureus- and K. pneumoniae-conditioned media
In this research, Pseudomonas aeruginosa underwent evolution in the supernatant of either S. aureus (SA) or K. pneumoniae (KP). Through this evolution process, we enriched a sufficient number of bacterial cells along with their corresponding proteins. Following 15 cultivation cycles, notable changes...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2025-05-21 | PXD059669 | Pride
Supernatant Laboratory evolution Proteomics K. pneumoniae S. aureus P. aeruginosa 
UnknownCulturally Adapted Guided Internet-Based Cognitive Behavioral Therapy for Hong Kong People With Depressive Symptoms: Randomized Controlled Trial.
Not available
S-EPMC11897664 | biostudies-literature
UnknownA therapist-guided internet-based cognitive behavioral therapy program for Hong Kong university students with psychological distress: A study protocol for a randomized controlled trial.
Not available
S-EPMC9826850 | biostudies-literature
UnknownA genome-wide association study of Chinese and English language phenotypes in Hong Kong Chinese children.
Not available
S-EPMC10973362 | biostudies-literature
TranscriptomicsGlobal gene expression change in the cerebellum of Niemann-Pick disease type C mice with deletion of Ccl3 or Purkinje neuron-specific NPC1 rescue
Macrophage inflammatory protein 1alpha/CCL3 protein is a known pro-inflammatory cytokine that can mediate chemotaxis of monocytes and promote cell degranulation. Ccl3 gene expression is elevated in the CNS and visceral tissue of many lysosomal storage disorders. The deletion of Ccl3 in a mouse model...
ORGANISM(S): Mus musculus 
2012-04-16 | E-GEOD-36119 | biostudies-arrayexpress
ProteomicsHuman Angiotensin-Converting Enzyme 2-Specific Benzothiazole Allosteric Inhibitor against Pan-Sarbecoviruses
Emerging SARS-CoV-2 variants of concern (VOCs) have demonstrated exceptional transmissibility and a strong dependence on the cellular receptor human angiotensin-converting enzyme 2 (hACE2). In this study, we present MB-32, a benzothiazole-based small molecule allosteric inhibitor of hACE2, w...
ORGANISM(S): Homo sapiens (Human) Sarbecovirus 
2026-05-01 | PXD075140 | Pride
Human Mb-32 Entry inhibtor Angiotensin-converting enzyme 2 Covid19 Allosteric inhibitor Sarbecovirus Benzothiazole Formaldehyde crosslinking 
ProteomicsProteomic study of baicalein effects on LPS-primed BV2 microglia
To comprehensively study the intracellular signaling changes and explore the underlying mechanisms of baicalein-mediated microglial responses, we employed systemic proteomic approach, using target-free SWATH mass spectra (SWATH-MS), focusing on intracellular proteins. BV2 cells were treated with LPS...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-14 | PXD030447 | Pride
Baicalein Microglia 
UnknownThe molecular classification of cancer-associated fibroblasts on a pan-cancer single-cell transcriptional atlas.
Not available
S-EPMC10751516 | biostudies-literature
UnknownDiscovery of Highly Potent Small Molecule Pan-Coronavirus Fusion Inhibitors.
Not available
S-EPMC10141620 | biostudies-literature
UnknownHighly Strong and Transparent Hydrogel Elastomers Microfabricated for 3D Microphysiological Systems.
Not available
S-EPMC12291088 | biostudies-literature
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