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Directed endocytosis mediates immune communication between an epithelial commensal microbe and the host
Commensal bacteria influence host physiology, including immune responses, without invading host tissues. We show that proteins from segmented filamentous bacteria (SFB), which are immunomodulatory commensal microbes, are transferred into intestinal epithelial cells by adhesion-directed endocytosis t...
ORGANISM(S): Mus musculus 
2019-01-10 | GSE124848 | GEO
Host-microbe communication via small molecule signals is often poorly understood at the molecular level. Under conditions of host stress, levels of the human opioid peptide dynorphin are elevated, triggering virulence in the opportunistic pathogenic bacterium Pseudomonas aeruginosa (PAO1) via an unk...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2017-04-03 | PXD006172 | Pride
We analyzed the effects of antibiotics using a popular model of gut microbiota depletion in mice by a cocktail of antibiotics. We combined intestinal transcriptome together with metagenomic analysis of the gut microbiota to develop a new bioinformatics approach that probes the links between microbia...
ORGANISM(S): Mus musculus 
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