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MetabolomicsMulti-omics analysis reveals microbiota-metabolite crosstalk in MASLD pathogenesis in a non-obese murine model

The rising global prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), including its severe form metabolic dysfunction-associated steatohepatitis (MASH), underscores the urgency to elucidate its pathophysiology. To investigate key metabolic interactions central to MASLD...

2026-03-13 | MTBLS14048 | MetaboLights
MetabolomicsUntargeted metabolomics profiling of esophageal tissues from a rat model of reflux esophagitis treated with Shunwei Jiangni Decoction

This dataset contains raw untargeted metabolomics data generated from esophageal tissue samples of rats in a reflux esophagitis (RE) model. The study aimed to characterize metabolic alterations associated with RE pathogenesis and to evaluate the regulatory effects of Shunwei Jiangni Decoction (SW...

2026-04-10 | MTBLS14112 | MetaboLights
ProteomicsType III CI Factors from wAlbB Induce Cytoplasmic Incompatibility via a Host Modification Mechanism
The widespread prevalence of the endosymbiotic bacterium Wolbachia among insect species relies on its ability to invade and manipulate host reproduction via several ways, among which cytoplasmic incompatibility (CI) is most studied. Two non-mutually exclusive models, the Host-Modification (HM) and t...
ORGANISM(S): Aedes albopictus 
2026-10-30 | PXD084067 | Pride
Cifb Subcelluar localization Testis Wolbachia Cifa Host-modification model Walbb Type iii cifs Toxin-antidote model Drosophila melanogaster Ci factors (cifs) Type iv cifs Aedes aegypti Early germine cells Male germline 
TranscriptomicsA mouse model of deregulation of the malt1 oncogene recapitulates the pathogenesis of human malt lymphoma
This SuperSeries is composed of the following subset Series: GSE25636: A mouse model of deregulation of the malt1 oncogene recapitulates the pathogenesis of human malt lymphoma [MouseSca1 dataset] GSE25637: A mouse model of deregulation of the malt1 oncogene recapitulates the pathogenesis of human m...
ORGANISM(S): Mus musculus 
2012-07-09 | E-GEOD-25639 | biostudies-arrayexpress
TranscriptomicsNative functions of the androgen receptor are essential to pathogenesis in a Drosophila model of spinobulbar muscular atrophy
Spinobulbar muscular atrophy (SBMA) is a neurodegenerative disease caused by expansion of a polyglutamine tract in the androgen receptor (AR). This mutation confers toxic function to AR through unknown mechanisms. Mutant AR toxicity requires binding of its hormone ligand, suggesting that pathogenesi...
ORGANISM(S): Drosophila melanogaster 
2010-09-23 | E-GEOD-23802 | biostudies-arrayexpress
UnknownN6-Methyladenosine RNA Modification in Host Cells Regulates Peste des Petits Ruminants Virus Replication.
Not available
S-EPMC10101086 | biostudies-literature
UnknownRegulatory Modules Involved in the Degradation and Modification of Host Cell Walls During Cuscuta campestris Invasion.
Not available
S-EPMC9298654 | biostudies-literature
TranscriptomicsMouse alveolar rhabdomyosarcoma and wild-type skeletal muscle
The highly aggressive muscle cancer alveolar rhabdomyosarcoma (ARMS) is one of the most common soft tissue sarcoma of childhood, yet the outcome for unresectable and metastatic disease is dismal and unchanged for nearly 3 decades. To better understand the pathogenesis of this disease and to facilita...
ORGANISM(S): Mus musculus 
2009-08-27 | E-GEOD-15489 | biostudies-arrayexpress
UnknownReal-time kinetics of restriction-modification gene expression after entry into a new host cell.
Not available
S-EPMC2377437 | biostudies-literature
TranscriptomicsA primate nigrostriatal atlas of neuronal vulnerability and resilience in a model of Parkinson’s disease
The degenerative process in Parkinson’s disease (PD) causes a progressive loss of dopaminergic neurons (DaNs) in the nigrostriatal system. Resolving the differences in neuronal susceptibility warrants an amenable PD model that, in comparison to post-mortem human specimens, controls for environmental...
ORGANISM(S): Macaca fascicularis 
2023-11-19 | E-MTAB-13437 | biostudies-arrayexpress
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