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TranscriptomicsGeneration of hematopoietic progenitor cell lines with myeloid and lymphoid potential using a conditional form of Hoxb8
Investigation of immune cell differentiation and function is limited by shortcomings of suitable and scalable experimental systems. Although forced expression of certain Hox genes allows immortalization of hematopoietic progenitor cells, their differentiation potential is limited to select myeloid l...
ORGANISM(S): Mus musculus 
2013-06-05 | E-GEOD-45759 | biostudies-arrayexpress
ProteomicsDifferential impact of LPS and LTA stimulation on differentiated bone marrow and Yolk sac Hoxb8 macrophages
The impact of LPS and LTA stimulation on differentiated bone marrow and Yolk sac Hoxb8 macrophages in comparison to untreated control cells was studied by global protein profiling using a bottom-up approach.
ORGANISM(S): Mus musculus (Mouse) 
2022-02-04 | PXD026922 | Pride
Lps Lc-ms/ms Hoxb8 Bone marrow Yolk sac Lta Macrophages 
UnknownCorticostriatal circuit defects in Hoxb8 mutant mice.
Not available
S-EPMC5970001 | biostudies-literature
ProteomicsFull proteome analysis of Hoxb8 immortalized murine myeloid progenitors knockout for CCDC134 and differentiated into macrophages
We recently identified CCDC134 as a novel regulator of TLR responses. To gain a comprehensive understanding of the effects of CCDC134 loss, we conducted total proteome analysis on control sgRen and sgCCDC134 Hoxb8 immortalized murine myeloid progenitors that were differentiated into macrophages. Int...
ORGANISM(S): Mus musculus (Mouse) 
2024-11-14 | PXD053042 | Pride
Ccdc134 Full proteome Hoxb8 macrophages 
UnknownDefining the Hoxb8 cell lineage during murine definitive hematopoiesis.
Not available
S-EPMC9124572 | biostudies-literature
GenomicsRNA sequencing of Hoxb8 yolk sac- and bone marrow-derived
RNA sequencing of Hoxb8 yolk sac- and bone marrow-derived
PRJNA736088 | ENA
UnknownHematopoietic origin of pathological grooming in Hoxb8 mutant mice.
Not available
S-EPMC2894573 | biostudies-literature
TranscriptomicsIdentification of HOXB8 and K LK11 expression levels as potential biomarkers to predict the effects of FOLFOX4 chemotherapy
To measure global gene expression in primary advanced colorectal cancer patients who have undergone fluorouracil, leucovorin and oxaliplatin (FOLFOX4) chemotherapy and screen valuable biomarkers to predict the effects of chemotherapy Samples from primary advanced colorectal cancer patients were col...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-69657 | biostudies-arrayexpress
UnknownDefective Hoxb8 microglia are causative for both chronic anxiety and pathological overgrooming in mice.
Not available
S-EPMC12815679 | biostudies-literature
UnknownHOXB8 mediates resistance to cetuximab in colorectal cancer cells through activation of the STAT3 pathway.
Not available
S-EPMC11522251 | biostudies-literature
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